PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12411410-5 2002 After 24 h of incubation, leptin (1-10 micro g ml(-1)) potently synergized with IFN-gamma (100 U ml(-1)) in nitric oxide (NO) release, evaluated as nitrite and nitrate (NO(x)), and prostaglandin E(2) (PGE(2)) production in culture medium. Nitrites 148-155 leptin Mus musculus 26-32 17935739-5 2007 For this purpose, the amount of stable nitrite, the end product of NO generation by activated chondrocytes, has been evaluated by Griess colorimetric reaction in culture medium of human primary chondrocytes and in the murine ATDC5 cell line stimulated with leptin (400 nM) and interferon-gamma (1 ng/ml), alone or in combination. Nitrites 39-46 leptin Mus musculus 257-263 17935739-9 2007 Pre-treatment with Wortmannin, LY 294002, PD 098,059 and SB 203580 caused a significant decrease in nitrite production, NOS type II protein expression and NOS type II mRNA expression induced by leptin and interferon-gamma co-stimulation. Nitrites 100-107 leptin Mus musculus 194-200