PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26161984-0 2015 Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment Epithelium. Nitrites 0-7 CD46 molecule Homo sapiens 52-56 26161984-2 2015 Herein we investigated the effect of nitrite modification of the extracellular matrix (ECM) as an in vitro model of "aging" and its effect on CD46 expression and vascular endothelial growth factor (VEGF) release in cocultured human retinal pigment epithelium (RPE). Nitrites 37-44 CD46 molecule Homo sapiens 142-146 26161984-8 2015 Nitrite modification of ECM reduced the expression of CD46 on ARPE-19 cells by 0.5-fold (P = 0.003) and increased VEGF release in ARPE-19 cells by 1.7-fold (P < 0.001). Nitrites 0-7 CD46 molecule Homo sapiens 54-58 26161984-10 2015 CONCLUSIONS: Nitrite modification of the ECM decreased CD46 expression and increased the release of VEGF from ARPE-19 cells. Nitrites 13-20 CD46 molecule Homo sapiens 55-59