PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20029546-0 2009 Vascular responses to nitrite are mediated by xanthine oxidoreductase and mitochondrial aldehyde dehydrogenase in the rat. Nitrites 22-29 aldehyde dehydrogenase 2 family member Rattus norvegicus 74-110 20543077-8 2010 These results suggest that ALDH2 plays an important role in the bioactivation of GTN and nitrite in the pulmonary and systemic vascular beds and that the reduction of nitrite to vasoactive NO does not play an important role in mediating vasodilator responses to GTN in the intact chest rat. Nitrites 89-96 aldehyde dehydrogenase 2 family member Rattus norvegicus 27-32 20029546-3 2009 It has been hypothesized that deoxyhemoglobin, xanthine oxidoreductase, mitochondrial aldehyde dehydrogenase, and other heme proteins can reduce nitrite to NO, but studies in the literature have not identified the mechanism in the intact rat, and several studies report no effect of inhibitors of xanthine oxidoreductase. Nitrites 145-152 aldehyde dehydrogenase 2 family member Rattus norvegicus 72-108 20029546-14 2009 The results of these studies suggest that nitrite can be reduced to vasoactive NO in the systemic vascular bed of the rat by xanthine oxidoreductase and mitochondrial aldehyde dehydrogenase and that the 2 pathways of nitrite activation act in a parallel manner. Nitrites 42-49 aldehyde dehydrogenase 2 family member Rattus norvegicus 153-189 16242127-4 2005 NO donors such as S-nitrosoglutathione (GSNO), S-nitroso-N-acetylpenicillamine, and 3-morpholinosydnonimine significantly increased the nitrite concentration while they inhibited the ALDH2 activity. Nitrites 136-143 aldehyde dehydrogenase 2 family member Rattus norvegicus 183-188