PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9307076-8 1997 Nitrite production was enhanced when the MDM were primed (pretreated) with gamma or alpha interferon or other immune mediators such as IL-4 and was reduced by the iNOS inhibitor, N-methyl-L-arginine (L-NMMA). Nitrites 0-7 interleukin 4 Homo sapiens 135-139 10233688-3 1999 Interferon-gamma (IFN-gamma) completely overcame the enhancement of serotonin release and suppression of nitrite production induced by IL-4. Nitrites 105-112 interleukin 4 Homo sapiens 135-139 10233688-4 1999 Over several experiments, with or without IL-4 and/or IFN-gamma, serotonin release correlated inversely with nitrite production. Nitrites 109-116 interleukin 4 Homo sapiens 42-46 8958048-3 1996 Interleukin-4 (IL-4) and interleukin-13 (IL-13) but not interleukin-10 (IL-10) inhibited both iNOS mRNA expression and nitrite release in A549 cells. Nitrites 119-126 interleukin 4 Homo sapiens 0-13 8985206-0 1997 Nitrite generation in interleukin-4-treated human macrophage cultures does not involve the nitric oxide synthase pathway. Nitrites 0-7 interleukin 4 Homo sapiens 22-35 8985206-2 1997 Recently, generation of nitrite in culture supernatants of human macrophages exposed to interferon-gamma and interleukin-4 (IFN-gamma/IL-4) was reported. Nitrites 24-31 interleukin 4 Homo sapiens 109-122 8985206-2 1997 Recently, generation of nitrite in culture supernatants of human macrophages exposed to interferon-gamma and interleukin-4 (IFN-gamma/IL-4) was reported. Nitrites 24-31 interleukin 4 Homo sapiens 134-138 8985206-8 1997 Nitrite accumulation in experiments with IFN-gamma/IL-4 in human monocytes appears to be an in vitro artifact produced by nitrate-reducing activities contained in cytokine preparations. Nitrites 0-7 interleukin 4 Homo sapiens 51-55 8958048-3 1996 Interleukin-4 (IL-4) and interleukin-13 (IL-13) but not interleukin-10 (IL-10) inhibited both iNOS mRNA expression and nitrite release in A549 cells. Nitrites 119-126 interleukin 4 Homo sapiens 15-19 7858061-2 1994 In addition to induce IgE production, IL-4 was found to elicit nitrite (NO2-) release by PBMC. Nitrites 63-70 interleukin 4 Homo sapiens 38-42 7530231-0 1994 Heterogenous nitrite production by IL-4-stimulated human monocytes and peripheral blood mononuclear cells. Nitrites 13-20 interleukin 4 Homo sapiens 35-39 7530231-1 1994 The capacity of human peripheral blood mononuclear cells and monocytes to generate nitrites, spontaneously or in response to Interleukin-4 was evaluated in vitro. Nitrites 83-91 interleukin 4 Homo sapiens 125-138 7530231-4 1994 The present data also indicated that addition of Interleukin-4 generally resulted in an increased nitrite production, that was potentiated by IFN-gamma, inactive alone. Nitrites 98-105 interleukin 4 Homo sapiens 49-62 7606802-2 1995 After 6 days of culture with IL-4, human monocytes released detectable amounts of nitrite and L-citrulline that were inhibited in the presence of nitro-L-arginine (1 mM). Nitrites 82-89 interleukin 4 Homo sapiens 29-33 7606802-3 1995 Incubation with an anti-CD23 mAb Fab fragment that suppressed the biological effect of CD23 led to a strong reduction (50 to 70%) of the IL-4-induced nitrite and L-citrulline production. Nitrites 150-157 interleukin 4 Homo sapiens 137-141 7606802-5 1995 Preactivation of human monocytes with IFN-gamma led to subsequent increased IL-4- and CD23-driven nitrite and L-citrulline productions that were also suppressed in the presence of either nitro-L-arginine or the anti-CD23 mAb Fab fragment. Nitrites 98-105 interleukin 4 Homo sapiens 76-80 7858061-3 1994 A marked correlation was observed between IgE secretion and nitrite release by PBMC stimulated with an optimal concentration of IL-4. Nitrites 60-67 interleukin 4 Homo sapiens 128-132 7511593-9 1994 In addition, IL-4 induced an increased secretion of nitrite by monocytes, that was potentiated by IFN-gamma and inhibited by L-NMMA. Nitrites 52-59 interleukin 4 Homo sapiens 13-17 16297873-3 2006 The data presented demonstrate that IL-4 alone can inhibit nitrite release in the presence and absence of IL-1beta and partially reverse the IL-1beta induced PGE2 release. Nitrites 59-66 interleukin 4 Homo sapiens 36-40 16297873-4 2006 When provided in combination, IL-4 and dynamic compression could further abrogate the IL-1beta induced nitrite and PGE2 release. Nitrites 103-110 interleukin 4 Homo sapiens 30-34