PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18539756-9 2008 Organ chamber experiments demonstrated that aortic relaxation induced by nitrite could be blocked by both hemoglobin and soluble guanylyl cyclase (sGC) inhibitor 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline-1-one (ODQ). Nitrites 73-80 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 121-145 18539756-9 2008 Organ chamber experiments demonstrated that aortic relaxation induced by nitrite could be blocked by both hemoglobin and soluble guanylyl cyclase (sGC) inhibitor 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline-1-one (ODQ). Nitrites 73-80 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 147-150 18539756-11 2008 These findings thus suggest that nitrite can be a precursor of EDRF and that sGC or other heme proteins inhibited by ODQ catalyze the reduction of nitrite to NO. Nitrites 147-154 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 77-80 23016570-6 2012 Treatment with either a nitric oxide scavenger or a soluble guanylyl cyclase (sGC) inhibitor diminished the beneficial effects of nitrite and decreased cGMP concentrations. Nitrites 130-137 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 52-76 23016570-6 2012 Treatment with either a nitric oxide scavenger or a soluble guanylyl cyclase (sGC) inhibitor diminished the beneficial effects of nitrite and decreased cGMP concentrations. Nitrites 130-137 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 78-81 23016570-7 2012 These results suggest that nitric oxide, generated from nitrite, is the molecule responsible for the effects of nitrite via the nitric oxide/sGC/cGMP pathway. Nitrites 56-63 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 141-144 23016570-7 2012 These results suggest that nitric oxide, generated from nitrite, is the molecule responsible for the effects of nitrite via the nitric oxide/sGC/cGMP pathway. Nitrites 112-119 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 141-144 26044183-8 2015 The presence of NO scavengers decreased the relaxation to nitrite in both WKY and SHR preparations while inhibition of soluble guanylyl cyclase (sGC) abolished the response, indicating that besides producing NO, nitrite also induces relaxation by directly activating the enzyme. Nitrites 212-219 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 119-143 26044183-8 2015 The presence of NO scavengers decreased the relaxation to nitrite in both WKY and SHR preparations while inhibition of soluble guanylyl cyclase (sGC) abolished the response, indicating that besides producing NO, nitrite also induces relaxation by directly activating the enzyme. Nitrites 212-219 guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus 145-148