PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24914193-7	2014	The ET-1+endothelin receptor type-A antagonist BQ-123 and the ETBR agonists sarafotoxin 6c and IRL-1620 caused less vasorelaxation and nitrate/nitrite production in RUPP than in Norm-Preg.	Nitrites	143-150	endothelin 1	Rattus norvegicus	4-8	
12051519-7	2002	Endothelin-1 additions diminished nitrate and nitrite levels in embryos from both control and n-stz diabetic rats, whereas bosentan stimulated nitrate and nitrite generation in those embryos.	Nitrites	46-53	endothelin 1	Rattus norvegicus	0-12	
16307975-8	2005	Our results showed that diabetic rats were associated with increased 8-OHdG, IL-6, and ET-1 decreased [nitrate+nitrite].	Nitrites	111-118	endothelin 1	Rattus norvegicus	87-91	
9039082-4	1997	Endothelin-1 significantly decreased the interleukin-1 beta-induced nitrite production by vascular smooth muscle cells in a dose-dependent manner (10(-11) to 10(-8) mol/L).	Nitrites	68-75	endothelin 1	Rattus norvegicus	0-12	
10564099-5	1999	ET-1 caused a 2.5-fold increase in eNOS protein in BPAECs, inhibitable with an endothelin B receptor antagonist, and an increase in eNOS mRNA and nitrite production.	Nitrites	146-153	endothelin 1	Rattus norvegicus	0-4	
7861129-4	1995	This inhibitor of ET-1 production was purified by gel-exclusion and ion-exchange chromatography as a 280-Da iron-containing molecule, able to release nitrites upon degradation.	Nitrites	150-158	endothelin 1	Rattus norvegicus	18-22	
8958563-2	1996	ET-1 inhibited the nitrite accumulation induced by a combination of interleukin-1 beta, tumor necrosis factor-alpha, and lipopolysaccharide in a concentration-dependent manner.	Nitrites	19-26	endothelin 1	Rattus norvegicus	0-4	
8958563-5	1996	These observations indicate that ET-1 inhibits cytokine-stimulated nitrite accumulation through the ETA receptor.	Nitrites	67-74	endothelin 1	Rattus norvegicus	33-37	
7615812-8	1995	The ET-1 effect does not involve nitric oxide since NG-monomethyl-L-arginine did not alter ET-1-induced RMIC contraction; in addition, ET-1 had only a minor effect on cGMP levels and no effect on nitrite production.	Nitrites	196-203	endothelin 1	Rattus norvegicus	4-8