PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9670978-7	1998	Inhibition of nitrite accumulation was associated with a fall in inducible NOS protein and an induction of heme oxygenase 1, correlating both dose dependently and temporally.	Nitrites	14-21	heme oxygenase 1	Mus musculus	107-123	
29145236-8	2017	Furthermore, nitrite pretreatment also showed significant alleviation of AMI-induced signal protein expressions of inflammatory factors of NF-K B and oxidative factors of Hsp 70 and HO-1.	Nitrites	13-20	heme oxygenase 1	Mus musculus	182-186	
25414768-10	2014	Transfection of siRNA targeting HO-1 reversed TI-I-174-mediated inhibition of nitrite production.	Nitrites	78-85	heme oxygenase 1	Mus musculus	32-36	
26553125-9	2016	The heme oxygenase-1 inhibitor zinc protoporphyrin attenuated the inhibitory effect of SCF4 on lipopolysaccharide-stimulated nitrite production and expression of inflammatory mediators, tumor necrosis factor alpha, and p-STAT1.	Nitrites	125-132	heme oxygenase 1	Mus musculus	4-20	
19183880-7	2009	Treatment with SnPP, a selective HO-1 inhibitor, reversed YL-I-108-mediated suppression of nitrite production, suggesting that HO-1 induction is implicated in the suppression of NO production by YL-I-108.	Nitrites	91-98	heme oxygenase 1	Mus musculus	127-131	
23942037-7	2013	Bilirubin production by HO-1 inducers correlated with their potency in inhibiting nitrite production after challenge with interferon-gamma (INF-gamma) or lipopolysaccharide (LPS).	Nitrites	82-89	heme oxygenase 1	Mus musculus	24-28	
23747519-0	2013	PG201 downregulates the production of nitrite by upregulating heme oxygenase-1 expression through the control of phosphatidylinositol 3-kinase and NF-E2-related factor 2.	Nitrites	38-45	heme oxygenase 1	Mus musculus	62-78	
23747519-8	2013	Furthermore, the results from an experiment involving a specific siRNA and chemical inhibitors for HO-1 showed that the PG201-mediated increase of the HO-1 protein contributed to the suppression of inducible nitric oxide synthase (iNOS) and nitrite production stimulated by lipopolysaccharide.	Nitrites	241-248	heme oxygenase 1	Mus musculus	99-103	
23747519-8	2013	Furthermore, the results from an experiment involving a specific siRNA and chemical inhibitors for HO-1 showed that the PG201-mediated increase of the HO-1 protein contributed to the suppression of inducible nitric oxide synthase (iNOS) and nitrite production stimulated by lipopolysaccharide.	Nitrites	241-248	heme oxygenase 1	Mus musculus	151-155	
24363996-13	2013	Moreover, the antioxidant enzyme expression of heme oxygenase-1 (HO-1) was elevated in MI mice treated with cLA and nitrite compared to untreated MI mice.	Nitrites	116-123	heme oxygenase 1	Mus musculus	47-63	
24363996-13	2013	Moreover, the antioxidant enzyme expression of heme oxygenase-1 (HO-1) was elevated in MI mice treated with cLA and nitrite compared to untreated MI mice.	Nitrites	116-123	heme oxygenase 1	Mus musculus	65-69	
22353229-9	2012	Treatment with zinc protoporphyrin, a selective inhibitor of HO-1, significantly reversed the ARGE-mediated inhibition of nitrite production (P < 0.05).	Nitrites	122-129	heme oxygenase 1	Mus musculus	61-65	
20399279-8	2010	Oral nitrite supplementation to colitis mice reversed colonic nitrite levels and TNF-alpha expression to that of normal control mice at day 3, resulting in the reduction of MPO activity as well as iNOS and HO-1 expressions in colonic tissues with clinical and histological improvements at day 7.	Nitrites	5-12	heme oxygenase 1	Mus musculus	206-210	
17300995-4	2007	Inhibition of HO-1 or scavenging of CO significantly reversed the inhibition of LPS-stimulated nitrite accumulation by tanshinone IIA, suggesting a novel role of HO-1 in the anti-inflammatory effect of tanshinone IIA.	Nitrites	95-102	heme oxygenase 1	Mus musculus	14-18	
15309569-9	2004	In addition, an inhibitor of HO-1 activity, chromium III mesoporhyrin (CrMP), attenuated the inhibitory activity of TauBr but not that of TauCl, as measured by nitrite accumulation.	Nitrites	160-167	heme oxygenase 1	Mus musculus	29-33