PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33143088-5 2020 Hindrance of inflammatory cytokine signaling is likely dependent on the hyperforin content of SJW extract, but recent data reveal that hypericin can also exert relevant protective effects, mediated by activation of the cyclic adenosine monophosphate (cAMP)/protein kinase cAMP-dependent (PKA)/adenosine monophosphate activated protein kinase (AMPK) pathway, against high-fat-diet-induced metabolic abnormalities. hypericin 135-144 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 343-347