PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20501911-3 2010 The kinetics of metabolite formation from phenacetin, tolbutamide, and alprazolam and midazolam, selected as substrates probes for CYP1A2, CYP2C9, and CYP3A4, respectively, were characterized in this in vitro system. Alprazolam 71-81 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 131-137 20080160-9 2010 In conclusion, Alprazolam, Bromazepam, Chlordiazepoxide, Clonazepam, Diazepam, Lorazepam, Nitrazepam, Oxazepam, Tetrazepam and Triazolam can be considered as safe drugs in term of their inability to induce PXR- and AhR-dependent cytochrome P450 enzymes CYP1A2 and CYP3A4. Alprazolam 15-25 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 253-259 9435993-20 1997 CYP2C19 and CYP1A2, the metabolism of several benzodiazepines, including alprazolam, bromazepam and diazepam. Alprazolam 73-83 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 12-18 10634135-0 1999 Simultaneous assessment of CYP3A4 and CYP1A2 activity in vivo with alprazolam and caffeine. Alprazolam 67-77 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 38-44 10634135-1 1999 Alprazolam (ALP) and caffeine (CAF) were suggested as probe drugs for the activities of CYP3A4 and CYP1A2, respectively. Alprazolam 0-10 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 99-105 10634135-1 1999 Alprazolam (ALP) and caffeine (CAF) were suggested as probe drugs for the activities of CYP3A4 and CYP1A2, respectively. Alprazolam 12-15 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 99-105