PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14978683-2 2004 Because the protein Huntingtin interacts with the homocysteine metabolism modulating enzyme cystathionine beta-synthase, we hypothesize that homocysteine promotes neurodegeneration in HD. Homocysteine 50-62 huntingtin Homo sapiens 20-30 14978683-2 2004 Because the protein Huntingtin interacts with the homocysteine metabolism modulating enzyme cystathionine beta-synthase, we hypothesize that homocysteine promotes neurodegeneration in HD. Homocysteine 141-153 huntingtin Homo sapiens 20-30 9466992-2 1998 We detected an interaction with cystathionine beta-synthase (CBS) [L-serine hydrolyase (adding homocysteine), EC 4.2.1.22], which was confirmed in vitro using His-tagged CBS expressed in Escherichia coli , which was able to specifically bind both rat and human full-length huntingtin. Homocysteine 95-107 huntingtin Homo sapiens 273-283