PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29735414-2	2018	In this study, Homocysteine (Hcy) is revealed to be a DAMP that activates adipocyte NLRP3 inflammasomes, participating in insulin resistance.	Homocysteine	29-32	NLR family pyrin domain containing 3	Homo sapiens	84-89	
34469206-0	2021	Adipocyte factor CTRP6 inhibits homocysteine-induced proliferation, migration, and dedifferentiation of vascular smooth muscle cells through PPARgamma/NLRP3.	Homocysteine	32-44	NLR family pyrin domain containing 3	Homo sapiens	151-156	
34469206-10	2021	The addition of GW9662 and rosiglitazone further demonstrated that overexpression of CTRP6 inhibited HCY-induced VSMC proliferation, migration, and dedifferentiation through PPARgamma/NLRP3 signaling.	Homocysteine	101-104	NLR family pyrin domain containing 3	Homo sapiens	184-189	
34469206-11	2021	In conclusion, CTRP6 inhibited HCY-induced proliferation, migration, and dedifferentiation of VSMCs through PPARgamma/NLRP3.	Homocysteine	31-34	NLR family pyrin domain containing 3	Homo sapiens	118-123	
29735414-3	2018	Hcy-induced activation of NLRP3 inflammasomes were observed in both adipocytes and adipose tissue macrophages (ATMs) and mediated insulin resistance.	Homocysteine	0-3	NLR family pyrin domain containing 3	Homo sapiens	26-31	
29735414-4	2018	Lysophosphatidylcholine (lyso-PC) acted as a second signal activator, mediating Hcy-induced adipocyte NLRP3 inflammasome activation.	Homocysteine	80-83	NLR family pyrin domain containing 3	Homo sapiens	102-107	
29735414-7	2018	This study demonstrated that Hcy activates adipose NLRP3 inflammasomes in an adipocyte lyso-PC-dependent manner and highlights the importance of the adipocyte NLRP3 inflammasome in insulin resistance.	Homocysteine	29-32	NLR family pyrin domain containing 3	Homo sapiens	51-56	
29735414-7	2018	This study demonstrated that Hcy activates adipose NLRP3 inflammasomes in an adipocyte lyso-PC-dependent manner and highlights the importance of the adipocyte NLRP3 inflammasome in insulin resistance.	Homocysteine	29-32	NLR family pyrin domain containing 3	Homo sapiens	159-164