PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26071314-8 2015 BMP-2 treatment in 5-AzadC-treated normal chondrocytes resulted in SOST upregulation, which was mediated through Smad 1/5/8 binding on the CpG region of SOST promoter. Decitabine 19-26 SMAD family member 1 Homo sapiens 113-121 31648327-6 2019 The pharmacologic restoration of SMAD1 expression by the demethylating agent decitabine (DAC) sensitizes cells to TGF-beta-induced apoptosis and reverses the growth of initially SMAD1- cell lines in ectopic and orthotopic models. Decitabine 77-87 SMAD family member 1 Homo sapiens 33-38 31648327-6 2019 The pharmacologic restoration of SMAD1 expression by the demethylating agent decitabine (DAC) sensitizes cells to TGF-beta-induced apoptosis and reverses the growth of initially SMAD1- cell lines in ectopic and orthotopic models. Decitabine 77-87 SMAD family member 1 Homo sapiens 178-183 31648327-6 2019 The pharmacologic restoration of SMAD1 expression by the demethylating agent decitabine (DAC) sensitizes cells to TGF-beta-induced apoptosis and reverses the growth of initially SMAD1- cell lines in ectopic and orthotopic models. Decitabine 89-92 SMAD family member 1 Homo sapiens 33-38 31648327-6 2019 The pharmacologic restoration of SMAD1 expression by the demethylating agent decitabine (DAC) sensitizes cells to TGF-beta-induced apoptosis and reverses the growth of initially SMAD1- cell lines in ectopic and orthotopic models. Decitabine 89-92 SMAD family member 1 Homo sapiens 178-183 31648327-8 2019 We further show that DAC restores SMAD1 expression and reduces the tumor burden in a novel patient-derived orthotopic xenograft model. Decitabine 21-24 SMAD family member 1 Homo sapiens 34-39 24178621-8 2014 Treatment with DAC led to increased expression of SMAD1, a transcription factor involved in TGF-beta/bone morphogenetic protein (BMP) signaling, previously shown to be epigenetically silenced in resistant diffuse large B-cell lymphoma. Decitabine 15-18 SMAD family member 1 Homo sapiens 50-55