PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7699577-5 1995 During hepatocarcinogenic process with an aromatic amine, the expression and induction of CYP1A2 decreased especially in preneoplastic liver cells as judged by the expression of a placental form of glutathione S-transferase. aromatic amine 42-56 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 90-96 9512925-2 1997 Furthermore, H2O2 (Km = 103 microM) was found to be highly effective in supporting the human microsomal CYP1A2 catalyzed metabolic activation of the heterocyclic aromatic amine 2-amino-3-methylimidazo (4,5-f) quinoline (IQ) to mutagenic metabolites and the DNA adduct formed was the same as that formed by the mixed-function oxidase catalyzed activation system. aromatic amine 162-176 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 104-110 9477228-0 1998 Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli. aromatic amine 24-38 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 84-103 1800893-5 1991 The aromatic amine 2-amino-anthracene elicited a weak response in the cell line XEMd-MZ which expressed CYP1A2. aromatic amine 4-18 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 104-110