PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2242386-4 1990 Furosemide, an inhibitor of Na+, K+, Cl- co-transport, reduced the 86Rb+ influx and the effect was partly additive to the effect of 2 mM Ba2+. Rubidium-86 67-72 bone area 2 Mus musculus 137-140 2242386-2 1990 Ba2+ (2 mM) significantly reduced the ouabain-resistant 86Rb+ influx, without affecting the ouabain-sensitive influx. Rubidium-86 56-61 bone area 2 Mus musculus 0-3 2242386-5 1990 When the islets were preincubated with Ba2+ (2 mM) the specific effect of 1 mM furosemide on the 86Rb+ influx was reduced, whereas, in acute experiments, Ba2+ (2 mM) did not affect the specific effect of furosemide on 86Rb+ influx. Rubidium-86 97-102 bone area 2 Mus musculus 39-42 2242386-5 1990 When the islets were preincubated with Ba2+ (2 mM) the specific effect of 1 mM furosemide on the 86Rb+ influx was reduced, whereas, in acute experiments, Ba2+ (2 mM) did not affect the specific effect of furosemide on 86Rb+ influx. Rubidium-86 218-223 bone area 2 Mus musculus 39-42 2242386-6 1990 86Rb+ efflux from preloaded islets was significantly reduced by 2 mM Ba2+ and during the first 5 min of ion efflux the effect of the combination of 2 mM Ba2+ and 1 mM furosemide was stronger than the effect of Ba2+ alone. Rubidium-86 0-5 bone area 2 Mus musculus 69-72 2242386-6 1990 86Rb+ efflux from preloaded islets was significantly reduced by 2 mM Ba2+ and during the first 5 min of ion efflux the effect of the combination of 2 mM Ba2+ and 1 mM furosemide was stronger than the effect of Ba2+ alone. Rubidium-86 0-5 bone area 2 Mus musculus 153-156 2242386-6 1990 86Rb+ efflux from preloaded islets was significantly reduced by 2 mM Ba2+ and during the first 5 min of ion efflux the effect of the combination of 2 mM Ba2+ and 1 mM furosemide was stronger than the effect of Ba2+ alone. Rubidium-86 0-5 bone area 2 Mus musculus 153-156 2242386-7 1990 The data show that Ba2+ reduces 86Rb+ fluxes in the beta-cells and suggest that this is mainly mediated by inhibition of K+ channels in the beta-cell plasma membrane. Rubidium-86 32-37 bone area 2 Mus musculus 19-22