PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26481430-5 2016 Using this validated computational method, we found that 1,3-propanediol (PDO) binds deep inside the AQP4 channel to inhibit that particular aquaporin efficaciously. 1,3-propanediol 57-72 aquaporin 4 Homo sapiens 101-105 26481430-5 2016 Using this validated computational method, we found that 1,3-propanediol (PDO) binds deep inside the AQP4 channel to inhibit that particular aquaporin efficaciously. 1,3-propanediol 74-77 aquaporin 4 Homo sapiens 101-105 27213050-0 2016 1,3-Propanediol binds inside the water-conducting pore of aquaporin 4: Does this efficacious inhibitor have sufficient potency? 1,3-propanediol 0-15 aquaporin 4 Homo sapiens 58-69 27213050-6 2016 We compute the binding affinities of 1,2-ethanediol (EDO) and 1,3-propanediol (PDO) inside the AQP4 conducting pore and identify the specificities of the interactions. 1,3-propanediol 62-77 aquaporin 4 Homo sapiens 95-99 27213050-9 2016 Considering the fact that PDO is classified by the US Food and Drug Administration as generally safe, we predict that 1,3-propanediol could be an effective drug for brain edema and other AQP4-correlated neurological conditions. 1,3-propanediol 118-133 aquaporin 4 Homo sapiens 187-191