PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7944563-1 1994 In this study, we evaluated the effects of the genetic polymorphism of ALDH2 (low Km aldehyde dehydrogenase) on toluene metabolism and determined biological exposure indices (BEIs) of the genotypes of ALDH2. Toluene 112-119 aldehyde dehydrogenase 2 family member Homo sapiens 71-76 7645026-1 1995 In this study, we evaluated the effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on the toluene metabolism. Toluene 130-137 aldehyde dehydrogenase 2 family member Homo sapiens 43-48 7645026-9 1995 The HA formation from toluene was significantly (p < 0.001) different among the genotypes of ALDH2. Toluene 22-29 aldehyde dehydrogenase 2 family member Homo sapiens 96-101 7645026-17 1995 In a multiple regression analysis, ALDH2 and the drinking habit were significantly (p < 0.01) associated with HA excretion after toluene exposure with and without correction for creatinine, and the corrected HA concentration was also significantly (p < 0.01) increased in the Ile/Val and Val/Val group of CYP1A1. Toluene 132-139 aldehyde dehydrogenase 2 family member Homo sapiens 35-40 9143096-12 1997 Lastly, genetic variations that result in deficiency of ALDH2, an enzyme involved in toluene metabolism, may increase the risks of toluene teratogenicity in at-risk individuals at lower levels of exposure. Toluene 85-92 aldehyde dehydrogenase 2 family member Homo sapiens 56-61 9143096-12 1997 Lastly, genetic variations that result in deficiency of ALDH2, an enzyme involved in toluene metabolism, may increase the risks of toluene teratogenicity in at-risk individuals at lower levels of exposure. Toluene 131-138 aldehyde dehydrogenase 2 family member Homo sapiens 56-61 7849865-1 1994 OBJECTIVES: To clarify the relation between the genetic polymorphism of ALDH2 (low Km aldehyde dehydrogenase) and toluene metabolism. Toluene 114-121 aldehyde dehydrogenase 2 family member Homo sapiens 72-77 7849865-20 1994 CONCLUSIONS: The HA concentrations of toluene workers with ALDH2 DD genotype were lower than those of the NN and ND genotypes when they were exposed to relatively high concentrations of toluene. Toluene 38-45 aldehyde dehydrogenase 2 family member Homo sapiens 59-64 7849865-20 1994 CONCLUSIONS: The HA concentrations of toluene workers with ALDH2 DD genotype were lower than those of the NN and ND genotypes when they were exposed to relatively high concentrations of toluene. Toluene 186-193 aldehyde dehydrogenase 2 family member Homo sapiens 59-64 8406909-6 1993 The alteration of toluene metabolism by the polymorphism of ALDH2 was not clear because the exposure levels of the workers to toluene were low. Toluene 18-25 aldehyde dehydrogenase 2 family member Homo sapiens 60-65 8406909-6 1993 The alteration of toluene metabolism by the polymorphism of ALDH2 was not clear because the exposure levels of the workers to toluene were low. Toluene 126-133 aldehyde dehydrogenase 2 family member Homo sapiens 60-65