PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31646826-0	2019	In vitro anticancer effects of esculetin against human leukemia cell lines involves apoptotic cell death, autophagy, G0/G1 cell cycle arrest and modulation of Raf/MEK/ERK signalling pathway.	esculetin	31-40	mitogen-activated protein kinase kinase 7	Homo sapiens	163-166	
31646826-12	2019	Esculetin could also block the Raf/MEK/ERK signalling pathway in leukemia cells in a concentration-dependent manner.	esculetin	0-9	mitogen-activated protein kinase kinase 7	Homo sapiens	35-38	
19428345-14	2009	Based on these studies, esculetin enhances the As(2)O(3)-provoked apoptosis by modulating the MEK/ERK and JNK pathways and reducing intracellular GSH levels.	esculetin	24-33	mitogen-activated protein kinase kinase 7	Homo sapiens	94-97