PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15297456-7 2004 Whereas UNG expression is significantly higher in proliferating as compared with nonproliferating cells, such as neurons, the levels of UNG mRNA were increased in brains of cystathionine beta-synthase knockout mice, a model for hyperhomocysteinemia, suggesting that one-carbon metabolism impairment and uracil misincorporation can induce the up-regulation of UNG expression. Carbon 270-276 cystathionine beta-synthase Mus musculus 173-200 29803556-3 2018 Redox homeostasis, free-radical detoxification and one-carbon metabolism (Methionine-Hcy-Folate cycle) require CBS and its deficiency leads to hyperhomocysteinemia (HHcy) causing retinovascular thromboembolism and eye-lens dislocation along with vascular cognitive impairment and dementia. Carbon 55-61 cystathionine beta-synthase Mus musculus 111-114 23439872-4 2013 Strain-dependent down-regulation of several key one-carbon metabolism genes, including methionine adenosyltransferase 1alpha (Mat1a), cystathionine-beta-synthase (Cbs), methylenetetrahydrofolate reductase (Mthfr), adenosyl-homocysteinase (Ahcy), and methylenetetrahydrofolate dehydrogenase 1 (Mthfd1), was observed. Carbon 52-58 cystathionine beta-synthase Mus musculus 163-166 12163655-2 2002 The present study was undertaken to assess the effect of elevated plasma total homocysteine caused by cystathionine beta-synthase deficiency on one-carbon metabolism in 10 homozygous mutant mice and 10 age- and sex-matched wild-type mice. Carbon 148-154 cystathionine beta-synthase Mus musculus 102-129 32383312-4 2021 Here we report that Cystathionine beta-synthase (CBS), a central enzyme in one-carbon metabolism, functionally interacts with the core circadian protein Cryptochrome1 (CRY1). Carbon 79-85 cystathionine beta-synthase Mus musculus 20-47 32383312-4 2021 Here we report that Cystathionine beta-synthase (CBS), a central enzyme in one-carbon metabolism, functionally interacts with the core circadian protein Cryptochrome1 (CRY1). Carbon 79-85 cystathionine beta-synthase Mus musculus 49-52 32383312-12 2021 We observed temporal variation in one-carbon and transsulfuration pathways attributable to CRY1 induced CBS activation. Carbon 38-44 cystathionine beta-synthase Mus musculus 104-107