PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32763432-8	2020	Transdermal administration with OVA@Eth-HA-GC/SF mats induced the serum anti-OVA-specific IgG and increased the expression of IFN-gamma, IL-2 and IL-6 by spleen cells in vivo.	Hyaluronic Acid	40-42	interleukin 6	Mus musculus	146-150	
28406731-5	2017	The group supplemented with high concentrations of hyaluronic acid appeared significantly better than control group for collagen, matrix metalloproteinase 1, interleukin (IL)-1beta, and IL-6 assay.	Hyaluronic Acid	51-66	interleukin 6	Mus musculus	186-190	
21855149-6	2011	In FLS, low molecular weight hyaluronan (HA)-induced TNFalpha and IL-6 production was increased by overexpression of beta-arrestin 1 but decreased by overexpression of beta-arrestin 2 demonstrating isoform specific regulation.	Hyaluronic Acid	29-39	interleukin 6	Mus musculus	66-70	
19781786-3	2009	In contrast to mice injected with LPS, mice exposed to hyaluronan prior to LPS had greatly decreased serum IL-6 and TNFalpha and were protected from symptoms of sepsis.	Hyaluronic Acid	55-65	interleukin 6	Mus musculus	107-111	
19781786-5	2009	Consistent with our findings in vivo, addition of hyaluronan to macrophages before LPS exposure significantly decreased the release of IL-6 and TNFalpha and this effect was not seen in macrophages from Cd44(-/-) mice.	Hyaluronic Acid	50-60	interleukin 6	Mus musculus	135-139	
18434414-4	2008	Hyaluronan fragments or hyaluronidase activated the NFkappaB pathway and induced Il6, Ccl4 and Ccl5 mRNA expression within 2 hours.	Hyaluronic Acid	0-10	interleukin 6	Mus musculus	81-84	
19574428-6	2009	Hyaluronan (HA), an endogenous ligand for toll-like receptor (TLR)-4, stimulated B cells, which infiltrates into wounds to produce interleukin-6 and transforming growth factor-beta through TLR4 in a CD19-dependent manner.	Hyaluronic Acid	0-10	interleukin 6	Mus musculus	131-144	
19574428-6	2009	Hyaluronan (HA), an endogenous ligand for toll-like receptor (TLR)-4, stimulated B cells, which infiltrates into wounds to produce interleukin-6 and transforming growth factor-beta through TLR4 in a CD19-dependent manner.	Hyaluronic Acid	12-14	interleukin 6	Mus musculus	131-144	
18854367-10	2009	Lower molecular weight hyaluronan induced IL-6 and MCP-1 production in PBMC, but high-molecular-weight hyaluronan did not induce IL-6 and MCP-1 production.	Hyaluronic Acid	23-33	interleukin 6	Mus musculus	42-46	
18854367-11	2009	An anti-CD44 antibody attenuated the induction of both IL-6 and MCP-1 in lower molecular weight hyaluronan-stimulated PBMC.	Hyaluronic Acid	96-106	interleukin 6	Mus musculus	55-59	
18854367-12	2009	In both TLR4 mutant and CD44-null mice, the induction of IL-6 by lower molecular weight hyaluronan stimulation was decreased.	Hyaluronic Acid	88-98	interleukin 6	Mus musculus	57-61	
15277700-6	2004	Intravenously infused HA was found in the bone marrow, where it bound endothelial cells and resident macrophages and increased expression of the hematopoiesis-supportive cytokines interleukin-1 and interleukin-6.	Hyaluronic Acid	22-24	interleukin 6	Mus musculus	198-211