PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25921269-1	2015	In this study, several novel sulfamides were synthesized and evaluated for their acetylcholine esterase (AChE) and human carbonic anhydrase I, and II isoenzymes (hCA I and II) inhibition profiles.	sulfamides	29-39	carbonic anhydrase 1	Homo sapiens	121-141	
16999776-0	2006	Examination of two independent kinetic assays for determining the inhibition of carbonic anhydrases I and II: structure-activity comparison of sulfamates and sulfamides.	sulfamides	158-168	carbonic anhydrase 1	Homo sapiens	80-108	
34387019-0	2021	Inhibition Profiles of Some Symmetric Sulfamides Derived from Phenethylamines on Human Carbonic Anhydrase I, and II Isoenzymes.	sulfamides	38-48	carbonic anhydrase 1	Homo sapiens	87-107	
34387019-4	2021	Some symmetric sulfamides compounds ( 11-18 ) demonstrated excellent inhibition effects against h CA I, and II isoenzymes.	sulfamides	15-25	carbonic anhydrase 1	Homo sapiens	98-102	
23394864-5	2013	The new sulfamides showed inhibition constants in the micro-submicromolar range, with one compound (N-(indane-1-yl)sulfamide) showing a Ki of 0.45muM against hCA I and of 1.07muM against hCA II.	sulfamides	8-18	carbonic anhydrase 1	Homo sapiens	158-163	
23266178-1	2013	A set of sulfamides and sulfamates were synthesized and tested against several isoforms of carbonic anhydrase: CA I, CA II, CA VII, CA XII and CA XIV.	sulfamides	9-19	carbonic anhydrase 1	Homo sapiens	111-115	
23266178-2	2013	The biological assays showed a broad range of inhibitory activity, and interesting results were found for several compounds in terms of activity (Ki <1mum) and selectivity: some aromatic sulfamides are active against CA I, CA II and/or CA VII; while they are less active in CA XII and CA XIV.	sulfamides	190-200	carbonic anhydrase 1	Homo sapiens	220-224