PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23858296-0	2013	Digitoxin induces apoptosis in cancer cells by inhibiting nuclear factor of activated T-cells-driven c-MYC expression.	Digitoxin	0-9	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	101-106	
23858296-3	2013	It has been reported that compounds resembling digitoxin are able to reduce c-MYC expression.	Digitoxin	47-56	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	76-81	
23858296-5	2013	We have therefore hypothesized that NFAT might mediate digitoxin effects on c-MYC mRNA message.	Digitoxin	55-64	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	76-81	
23858296-7	2013	RESULTS: Here we show that within the 1(st) h following treatment with digitoxin, a significant reduction in c-MYC mRNA occurs.	Digitoxin	71-80	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	109-114	
23858296-12	2013	Using c-MYC chromatin immune precipitation, we find that digitoxin inhibits interaction of NFAT1 with the proximal c-MYC promoter.	Digitoxin	57-66	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	6-11	
23858296-12	2013	Using c-MYC chromatin immune precipitation, we find that digitoxin inhibits interaction of NFAT1 with the proximal c-MYC promoter.	Digitoxin	57-66	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	115-120	
23858296-13	2013	CONCLUSIONS: These results suggest that the carcinotoxic activity of digitoxin includes suppression of NFAT-driven c-MYC expression.	Digitoxin	69-78	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	115-120