PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	111-113	TNF superfamily member 10	Homo sapiens	183-188	
28511914-0	2017	Digitoxin increases sensitivity of glioma stem cells to TRAIL-mediated apoptosis.	Digitoxin	0-9	TNF superfamily member 10	Homo sapiens	56-61	
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	100-109	TNF superfamily member 10	Homo sapiens	144-181	
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	100-109	TNF superfamily member 10	Homo sapiens	183-188	
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	100-109	TNF superfamily member 10	Homo sapiens	238-243	
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	111-113	TNF superfamily member 10	Homo sapiens	144-181	
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	111-113	TNF superfamily member 10	Homo sapiens	238-243	
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	231-233	TNF superfamily member 10	Homo sapiens	144-181	
28511914-3	2017	This study takes glioma stem cells (GSCs) as the subject and focuses on the sensitization effect of digitoxin (DT) on the apoptosis mediated by TNF-related apoptosis-inducing ligand (TRAIL) to prove that the combination therapy of DT and TRAIL has a more active effect of inducing GSCs apoptosis.	Digitoxin	231-233	TNF superfamily member 10	Homo sapiens	183-188	
28511914-7	2017	In conclusion, DT had a sensitization effect on GSCs apoptosis mediated by TRAIL.	Digitoxin	15-17	TNF superfamily member 10	Homo sapiens	75-80	
24045365-0	2014	Digitoxin sensitizes glioma cells to TRAIL-mediated apoptosis by upregulation of death receptor 5 and downregulation of survivin.	Digitoxin	0-9	TNF superfamily member 10	Homo sapiens	37-42	
24045365-3	2014	Here, we have shown that digitoxin (DT), a clinically approved cardiac glycoside for heart failure, can induce TRAIL-mediated apoptosis of glioblastoma cells.	Digitoxin	25-34	TNF superfamily member 10	Homo sapiens	111-116	
24045365-3	2014	Here, we have shown that digitoxin (DT), a clinically approved cardiac glycoside for heart failure, can induce TRAIL-mediated apoptosis of glioblastoma cells.	Digitoxin	36-38	TNF superfamily member 10	Homo sapiens	111-116	
24045365-4	2014	DT in noncytotoxic doses (20 nmol/l) can increase TRAIL-induced apoptosis in TRAIL-resistant U87MG glioblastoma cells.	Digitoxin	0-2	TNF superfamily member 10	Homo sapiens	50-55	
24045365-4	2014	DT in noncytotoxic doses (20 nmol/l) can increase TRAIL-induced apoptosis in TRAIL-resistant U87MG glioblastoma cells.	Digitoxin	0-2	TNF superfamily member 10	Homo sapiens	77-82	
24045365-6	2014	Moreover, silencing survivin with small interfering RNAs sensitized glioma cells to TRAIL-induced apoptosis, underscoring the functional role of survivin depletion in the TRAIL-sensitizing actions of DT.	Digitoxin	200-202	TNF superfamily member 10	Homo sapiens	84-89	
24045365-6	2014	Moreover, silencing survivin with small interfering RNAs sensitized glioma cells to TRAIL-induced apoptosis, underscoring the functional role of survivin depletion in the TRAIL-sensitizing actions of DT.	Digitoxin	200-202	TNF superfamily member 10	Homo sapiens	171-176	
24045365-7	2014	We demonstrate that inactivation of survivin and death receptor 5 expression by DT is sufficient to restore TRAIL sensitivity in resistant glioma cells.	Digitoxin	80-82	TNF superfamily member 10	Homo sapiens	108-113	
24045365-8	2014	Our results suggest that combining DT with TRAIL treatments may be useful in the treatment of TRAIL-resistant glioma cells.	Digitoxin	35-37	TNF superfamily member 10	Homo sapiens	94-99