PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26691294-1	2016	BACKGROUND: The cardiac glycoside digitoxin preferentially inhibits the growth of breast cancer cells and targets the Erk pathway.	Digitoxin	34-43	mitogen-activated protein kinase 1	Homo sapiens	118-121	
28410215-7	2017	Exposure to DT also reduced hypoxia-induced activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway.	Digitoxin	12-14	mitogen-activated protein kinase 1	Homo sapiens	62-103	
28035421-6	2017	Digitoxin and sorafenib synergistically inhibited cell viability, but did not inhibit migration, which was potentially mediated by suppression of ERK and hypoxia signaling.	Digitoxin	0-9	mitogen-activated protein kinase 1	Homo sapiens	146-149	
28035421-7	2017	In downstream signaling pathways, the activity of ERK was synergistically suppressed by combinatorial treatment of HepG2 and BEL-7402 cells with sorafenib and digitoxin.	Digitoxin	159-168	mitogen-activated protein kinase 1	Homo sapiens	50-53	
26691294-8	2016	Digitoxin activates expression of Erk pathway genes and suppresses expression of IAP genes.	Digitoxin	0-9	mitogen-activated protein kinase 1	Homo sapiens	34-37	
26691294-11	2016	CONCLUSION: Digitoxin appears to act through the Erk and stress response pathways and is worthwhile to study to prevent and treat cancer.	Digitoxin	12-21	mitogen-activated protein kinase 1	Homo sapiens	49-52