PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22972308-0 2012 Minocycline and fluorocitrate suppress spinal nociceptive signaling in intrathecal IL-1beta-induced thermal hyperalgesic rats. fluorocitrate 16-29 interleukin 1 beta Rattus norvegicus 83-91 22972308-6 2012 Minocycline, fluorocitrate, or SB203580 pretreatment suppressed this IL-1beta-upregulated P-p38 MAPK mainly in microglia and iNOS mainly in astrocytes; minocycline exhibited the most potent effect. fluorocitrate 13-26 interleukin 1 beta Rattus norvegicus 69-77 22972308-7 2012 Minocycline and fluorocitrate pretreatment abrogated IL-1beta-induced NO release and thermal hyperalgesia in rats. fluorocitrate 16-29 interleukin 1 beta Rattus norvegicus 53-61 22972308-8 2012 In conclusion, minocycline, fluorocitrate, and SB203580 effectively suppressed the IL-1beta-induced central sensitization and hyperalgesia in rats. fluorocitrate 28-41 interleukin 1 beta Rattus norvegicus 83-91 29678208-13 2018 Moreover, microinjection of fluorocitrate into the TGs completely blocked TMJ inflammation-induced activation of SGCs and the upregulation of IL-1beta and COX-2 in the SGCs, and phospho-CREB and Nav1.7 in the neurons and alleviated inflammation-induced TMJ hypernociception. fluorocitrate 28-41 interleukin 1 beta Rattus norvegicus 142-150 20587056-13 2010 The enhanced mRNA expression (B1R, IL-1beta, TNF-alpha, TRPV1) and Iba-1 immunoreactivity in the STZ spinal cord were normalized by fluorocitrate or minocycline, yet B1R binding sites were reduced by 38%. fluorocitrate 132-145 interleukin 1 beta Rattus norvegicus 35-43