PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10381197-0 1999 Salicylate promotes myeloperoxidase-initiated LDL oxidation: antagonization by its metabolite gentisic acid. Salicylates 0-10 myeloperoxidase Homo sapiens 20-35 10381197-3 1999 Taking into consideration, that monophenolic compounds are able to form phenoxyl radicals in presence of peroxidases, we have tested salicylate, in its ability to act as a prooxidant in the MPO system. Salicylates 133-143 myeloperoxidase Homo sapiens 190-193 10381197-5 1999 Exposure of LDL preparations to MPO in presence of salicylate revealed that the drug could act as a catalyst of lipid oxidation in LDL. Salicylates 51-61 myeloperoxidase Homo sapiens 32-35 10381197-10 1999 The results suggest that salicylate could act like tyrosine via a phenoxyl radical as a catalyst of LDL oxidative modification by MPO. Salicylates 25-35 myeloperoxidase Homo sapiens 130-133 6291348-11 1982 Salicylates and arylacetic acid derivatives, such as naproxen, also decreased MPO-CL. Salicylates 0-11 myeloperoxidase Homo sapiens 78-81 8006021-10 1994 Purified human myeloperoxidase and xanthine oxidase plus hypoxanthine hydroxylated salicylate to produce 2,5-dihydroxybenzoate. Salicylates 83-93 myeloperoxidase Homo sapiens 15-30 34510275-6 2021 However, one exception is salicylate, a very potent inhibitor of the neutrophilic enzyme, myeloperoxidase, the inhibition of which leads to reduced production of the inflammatory mediator, hypochlorous acid, and inhibition of the inflammation associated with rheumatoid arthritis. Salicylates 26-36 myeloperoxidase Homo sapiens 90-105