PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28712868-0	2017	Salicylates promote mitochondrial biogenesis by regulating the expression of PGC-1alpha in murine 3T3-L1 pre-adipocytes.	Salicylates	0-11	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	77-87	
28712868-6	2017	In this study, we assessed the effects of salicylate on the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) signaling pathway and mitochondrial biogenesis in pre-adipocytes.	Salicylates	42-52	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	60-127	
28712868-6	2017	In this study, we assessed the effects of salicylate on the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) signaling pathway and mitochondrial biogenesis in pre-adipocytes.	Salicylates	42-52	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	129-139	
28712868-7	2017	Our findings demonstrate that treatment with salicylate promoted the expression of PGC-1alpha and its downstream targets nuclear respiratory factor 1 (NRF1) and mitochondrial transcription factor A (TFAM).	Salicylates	45-55	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	83-93	
28712868-8	2017	Importantly, salicylate treatment significantly increased the number of mDNA, citrate synthase activity, expression of respiratory chain complex I, and mitochondrial mass, which were suppressed by the specific AMPK inhibitor Compound C. Indeed, salicylate treatment induced the phosphorylation of AMPK, which was involved in the induction of PGC-1alpha, NRF1, and TFAM.	Salicylates	13-23	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	342-352	
28712868-8	2017	Importantly, salicylate treatment significantly increased the number of mDNA, citrate synthase activity, expression of respiratory chain complex I, and mitochondrial mass, which were suppressed by the specific AMPK inhibitor Compound C. Indeed, salicylate treatment induced the phosphorylation of AMPK, which was involved in the induction of PGC-1alpha, NRF1, and TFAM.	Salicylates	245-255	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	342-352	
28712868-9	2017	Importantly, inhibition of PGC-1alpha expression using PGC-1alpha small RNA interference abolished the effects of salicylate on mitochondrial biogenesis.	Salicylates	114-124	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	27-37	
28712868-9	2017	Importantly, inhibition of PGC-1alpha expression using PGC-1alpha small RNA interference abolished the effects of salicylate on mitochondrial biogenesis.	Salicylates	114-124	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	55-65