PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12538810-2	2003	We demonstrated that salicylate inhibits PGHS-1 and -2 with a potency inversely related to ambient hydroperoxide concentrations.	Salicylates	21-31	prostaglandin-endoperoxide synthase 1	Homo sapiens	41-54	
16021964-5	2005	It is hypothesized that meloxicam loosely binds to the cyclooxygenase-1 (COX-1) enzyme and salicylate can easily replace it.	Salicylates	91-101	prostaglandin-endoperoxide synthase 1	Homo sapiens	55-71	
16021964-5	2005	It is hypothesized that meloxicam loosely binds to the cyclooxygenase-1 (COX-1) enzyme and salicylate can easily replace it.	Salicylates	91-101	prostaglandin-endoperoxide synthase 1	Homo sapiens	73-78	
12538810-3	2003	Salicylate inhibition of PGHS-1 was prevented by 12-hydroperoxyeicosatetraenoic acid (12-HPETE).	Salicylates	0-10	prostaglandin-endoperoxide synthase 1	Homo sapiens	25-31	
7872783-5	1995	Accordingly, we prepared and tested eight different acyl salicylates as inhibitors of human (h) PGHS-1 and -2 expressed transiently in cos-1 cells.	Salicylates	57-68	prostaglandin-endoperoxide synthase 1	Homo sapiens	96-109	
15035793-1	2003	Paracetamol and salicylate are weak inhibitors of both isolated cyclooxygenase-1 (COX-1) and COX-2 but are potent inhibitors of prostaglandin (PG) synthesis in intact cells if low concentrations of arachidonic acid are available.	Salicylates	16-26	prostaglandin-endoperoxide synthase 1	Homo sapiens	64-80	
15035793-1	2003	Paracetamol and salicylate are weak inhibitors of both isolated cyclooxygenase-1 (COX-1) and COX-2 but are potent inhibitors of prostaglandin (PG) synthesis in intact cells if low concentrations of arachidonic acid are available.	Salicylates	16-26	prostaglandin-endoperoxide synthase 1	Homo sapiens	82-87	
15035793-4	2003	Therefore, paracetamol and salicylate may selectively inhibit PG synthesis involving COX-2 because the lower flux through this pathway produces lesser levels of the hydroperoxide, PGG(2), than the pathway involving COX-1.	Salicylates	27-37	prostaglandin-endoperoxide synthase 1	Homo sapiens	215-220	
7965814-3	1994	All NSAIDs except salicylate had appreciable apparent affinities (IC50 < or = 100 microM) for hPGHS-1.	Salicylates	18-28	prostaglandin-endoperoxide synthase 1	Homo sapiens	97-104