PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30181664-4	2018	METHODS: The decrease of O-GlcNAcylation by alloxan, an OGT inhibitor, and increase by NAG-thiazolines (NAG-Ae), an O-GlcNAcase inhibitor were tested to investigate the effects of O-GlcNAc alteration on AD like neurodegeneration in SK-N-SH cells.	Alloxan	44-51	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	56-59	
30181664-4	2018	METHODS: The decrease of O-GlcNAcylation by alloxan, an OGT inhibitor, and increase by NAG-thiazolines (NAG-Ae), an O-GlcNAcase inhibitor were tested to investigate the effects of O-GlcNAc alteration on AD like neurodegeneration in SK-N-SH cells.	Alloxan	44-51	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	25-33	
20640461-5	2011	Here, we describe the synthesis of novel UDP-GlcNAc/UDP analogues and evaluate their inhibitory properties and structural binding modes in vitro alongside alloxan, a previously reported weak OGT inhibitor.	Alloxan	155-162	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	191-194	
18949387-8	2008	Of note, alloxan, an O-N-acetylglucosamine transferase inhibitor, which prevented the glucosamine-induced O-GlcNAc modification, abrogated the suppressive effect of glucosamine on MCP-1 and ICAM-1 expression (p<0.05 at 0.5 mM).	Alloxan	9-16	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	106-114	
12054585-4	2002	In isolated pancreatic islets, alloxan almost completely blocked both glucosamine-induced and STZ-induced protein O-GlcNAcylation, suggesting that alloxan indeed was inhibiting (OGT).	Alloxan	31-38	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	178-181	
12054585-4	2002	In isolated pancreatic islets, alloxan almost completely blocked both glucosamine-induced and STZ-induced protein O-GlcNAcylation, suggesting that alloxan indeed was inhibiting (OGT).	Alloxan	147-154	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	178-181	
12054585-5	2002	In order to show definitively that alloxan was inhibiting OGT activity, recombinant OGT was incubated with 0-10 mM alloxan, and OGT activity was measured directly by quantitating UDP-[(3)H]-GlcNAc incorporation into the recombinant protein substrate, nucleoporin p62.	Alloxan	35-42	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	58-61	
12054585-5	2002	In order to show definitively that alloxan was inhibiting OGT activity, recombinant OGT was incubated with 0-10 mM alloxan, and OGT activity was measured directly by quantitating UDP-[(3)H]-GlcNAc incorporation into the recombinant protein substrate, nucleoporin p62.	Alloxan	35-42	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	84-87	
12054585-5	2002	In order to show definitively that alloxan was inhibiting OGT activity, recombinant OGT was incubated with 0-10 mM alloxan, and OGT activity was measured directly by quantitating UDP-[(3)H]-GlcNAc incorporation into the recombinant protein substrate, nucleoporin p62.	Alloxan	35-42	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	84-87	
12054585-6	2002	Under these conditions, OGT activity was completely inhibited by 1 mM alloxan with half-maximal inhibition achieved at a concentration of 0.1 mM alloxan.	Alloxan	70-77	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	24-27	
12054585-6	2002	Under these conditions, OGT activity was completely inhibited by 1 mM alloxan with half-maximal inhibition achieved at a concentration of 0.1 mM alloxan.	Alloxan	145-152	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	24-27	
12054585-7	2002	Together, these data demonstrate that alloxan is an inhibitor of OGT, and as such, is the first OGT inhibitor described.	Alloxan	38-45	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	65-68	
12054585-7	2002	Together, these data demonstrate that alloxan is an inhibitor of OGT, and as such, is the first OGT inhibitor described.	Alloxan	38-45	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	96-99