PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20309867-1 2010 OBJECTIVE: Previous studies have revealed a phosphatase and tensin homolog (PTEN)-dependent interaction between the sphingolipid agonist dihydrosphingosine 1-phosphate (dhS1P) and the transforming growth factor beta/Smad3 signaling pathway. Sphingolipids 116-128 phosphatase and tensin homolog Homo sapiens 76-80 18482992-12 2008 PTEN-mediated cross-talk between the sphingolipid and TGF-beta signaling pathways may play an important role in physiological and pathological TGF-beta signaling. Sphingolipids 37-49 phosphatase and tensin homolog Homo sapiens 0-4 35331214-11 2022 Furthermore, aggressive-variant prostate cancer (AVPC), defined as 2 or more aberrations in TP53, RB1 and/or PTEN, was associated with elevated sphingolipids. Sphingolipids 144-157 phosphatase and tensin homolog Homo sapiens 109-113 32823607-6 2020 In conclusion, GA-induced c-Src activation is a key inductive event for the formation of inactive Rac1-p-CK2alpha (Tyr 255) complexes, which disturbed lipid raft compartment of PI3K and PTEN molecules by impairing Akt-regulated GLUT-1-mediated sphingolipid synthesis, and finally resulting in inhibition of TSC cell invasion. Sphingolipids 244-256 phosphatase and tensin homolog Homo sapiens 186-190 23239114-5 2013 In conclusion, rather modest changes in sphingolipids are correlated with the activation of PTEN and MAPK(ERK1/2) signaling proteins in human uterine leiomyomas. Sphingolipids 40-53 phosphatase and tensin homolog Homo sapiens 92-96