PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33226447-11	2021	SMS1 inhibition disrupted sphingolipid metabolism via accumulating ceramide and decreasing sphingomyelin, inducing mitochondrial dysfunction and oxidative stress, and decreasing Ras activity in resistant cells.	Sphingolipids	26-38	sphingomyelin synthase 1	Homo sapiens	0-4	
31114500-0	2019	Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma.	Sphingolipids	66-78	sphingomyelin synthase 1	Homo sapiens	0-24	
31114500-0	2019	Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma.	Sphingolipids	66-78	sphingomyelin synthase 1	Homo sapiens	26-30	
28078595-1	2017	Sphingomyelin synthases 1 and 2 convert the anti-oncometabolite ceramide to sphingomyelin, the most abundant sphingolipid in plasma membrane.	Sphingolipids	109-121	sphingomyelin synthase 1	Homo sapiens	0-31	
28087695-1	2017	This study investigates the consequences of elevating sphingomyelin synthase 1 (SMS1) activity, which generates the main mammalian sphingolipid, sphingomyelin.	Sphingolipids	131-143	sphingomyelin synthase 1	Homo sapiens	54-78	
28087695-1	2017	This study investigates the consequences of elevating sphingomyelin synthase 1 (SMS1) activity, which generates the main mammalian sphingolipid, sphingomyelin.	Sphingolipids	131-143	sphingomyelin synthase 1	Homo sapiens	80-84	
28988346-12	2018	In addition, the expression of specific enzymes of sphingolipid metabolism, dihydroceramide desaturase 1 and sphingomyelin synthase 1, was increased in the PBMCs of individuals with type 2 diabetes.	Sphingolipids	51-63	sphingomyelin synthase 1	Homo sapiens	109-133	
24960545-7	2014	We found upregulation of specific sphingolipid enzymes, namely sphingomyelin synthase 1 (SMS1), sphingomyelinase 3 (SMPD3), and glucosylceramide synthase (GCS) in the endometrium of endometriotic women with corresponding increased GlcCer, decreased sphingomyelin levels, and decreased apoptosis in the endometrium.	Sphingolipids	34-46	sphingomyelin synthase 1	Homo sapiens	63-87	
24960545-7	2014	We found upregulation of specific sphingolipid enzymes, namely sphingomyelin synthase 1 (SMS1), sphingomyelinase 3 (SMPD3), and glucosylceramide synthase (GCS) in the endometrium of endometriotic women with corresponding increased GlcCer, decreased sphingomyelin levels, and decreased apoptosis in the endometrium.	Sphingolipids	34-46	sphingomyelin synthase 1	Homo sapiens	89-93