PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10770748-6	2000	Strains with deletions of SYR3/ELO2 and ELO3 were resistant to syringomycin E, and lipid analyses of both mutants revealed shortened fatty acid chains and lower levels of sphingolipids.	Sphingolipids	171-184	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	40-44	
15638242-5	2004	ELO3 encodes an enzyme involved in sphingolipid synthesis required for long-chain FA synthesis.	Sphingolipids	35-47	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	0-4	
12684378-6	2003	The Elo3 protein is necessary for synthesis of C(26)-CoA, which in wild-type yeast is a source of C(26) fatty acyls found in the ceramide moieties of all sphingolipids.	Sphingolipids	154-167	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	4-8	
12477802-4	2002	Mutations suppressing the rvs161delta-related salt sensitivity all occurred in genes required for sphingolipid biosynthesis: FEN1, SUR4, SUR2, SUR1, and IPT1.	Sphingolipids	98-110	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	131-135	
9211877-10	1997	Null mutations in ELO3 result in accumulation of labeled precursors into inositol phosphoceramide, with little labeling in the more complex mannosylated sphingolipids, whereas disruption of ELO2 results in reduced levels of all sphingolipids.	Sphingolipids	228-241	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	18-22	
9211877-0	1997	ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.	Sphingolipids	124-136	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	9-13	
30604175-3	2019	To reveal how AtBI-1 regulates sphingolipid synthesis, we screened yeast sphingolipid-deficient mutants and identified yeast ELO2 and ELO3 as novel enzymes that are essential for AtBI-1 function.	Sphingolipids	31-43	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	134-138	
20709688-5	2010	Under the AUR1-repressive conditions, the ELO3 mutant showed reduction in the complex sphingolipid levels and the accumulation of ceramide, like wild-type cells.	Sphingolipids	86-98	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	42-46	
24395234-0	2014	Sphingolipid biosynthetic pathway genes FEN1 and SUR4 modulate amphotericin B resistance.	Sphingolipids	0-12	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	49-53	
24395234-1	2014	Deletants of the sphingolipid biosynthetic pathway genes FEN1 and SUR4 of Saccharomyces cerevisiae, as well as deletants of their orthologs in Candida albicans, were found to be 2- to 5-fold-more sensitive to amphotericin B (AmB) than parent strains.	Sphingolipids	17-29	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	66-70	
22808036-6	2012	Five suppressor genes were identified (SUR4, ISC1, IPT1, SKN1, and FEN1) and all are involved in sphingolipid metabolism.	Sphingolipids	97-109	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	39-43	
17393212-5	2007	The erg2erg24 double mutant can be suppressed by mutations in the sphingolipid gene ELO3 but not ELO2.	Sphingolipids	66-78	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	84-88	
19286982-10	2009	Altering sphingolipid metabolism by deleting the very-long-chain fatty acid elongase SUR4 reinitiates transporter endocytosis in rvs161 and rvs161 endo(-) cells.	Sphingolipids	9-21	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	85-89	
19254955-4	2009	Recessive mutations in the sphingolipid pathway, such as deletion of the very long-chain fatty acid elongase, Sur4, suppress the osmotic growth defect of rvs161 cells.	Sphingolipids	27-39	fatty acid elongase ELO3	Saccharomyces cerevisiae S288C	110-114