PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27901468-5 2016 In fh mutants, iron accumulation in the nervous system enhances the synthesis of sphingolipids, which in turn activates 3-phosphoinositide dependent protein kinase-1 (Pdk1) and myocyte enhancer factor-2 (Mef2) to trigger neurodegeneration of adult photoreceptors. Sphingolipids 81-94 3-phosphoinositide dependent protein kinase 1 Homo sapiens 120-165