PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19209467-1 2009 PURPOSE OF REVIEW: Expression of defective cystic fibrosis transmembrane conductance regulator (CFTR), the cause for cystic fibrosis, affects fatty acid, cholesterol and sphingolipid metabolism. Sphingolipids 170-182 cystic fibrosis transmembrane conductance regulator Mus musculus 43-94 19209467-1 2009 PURPOSE OF REVIEW: Expression of defective cystic fibrosis transmembrane conductance regulator (CFTR), the cause for cystic fibrosis, affects fatty acid, cholesterol and sphingolipid metabolism. Sphingolipids 170-182 cystic fibrosis transmembrane conductance regulator Mus musculus 96-100 19209467-3 2009 RECENT FINDINGS: Recent observations implicate CFTR, in addition to known effects on fatty acid and cholesterol metabolism, in the regulation of sphingolipid metabolism and suggest that this pathway is relevant to inflammation and infection. Sphingolipids 145-157 cystic fibrosis transmembrane conductance regulator Mus musculus 47-51 19209467-9 2009 SUMMARY: Expression of defective CFTR has profound effects on fatty acid, cholesterol and sphingolipid metabolism, for which mechanisms are currently poorly understood. Sphingolipids 90-102 cystic fibrosis transmembrane conductance regulator Mus musculus 33-37 24500283-3 2014 In addition, CFTR-deficient cells and mouse models have been reported to have altered sphingolipid levels. Sphingolipids 86-98 cystic fibrosis transmembrane conductance regulator Mus musculus 13-17 25006445-2 2014 Cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel expressed in both epithelial and endothelial cells, regulates the organization of tight junctions between epithelial cells and has also been implicated in the transport of sphingosine-1 phosphate (S1P), a vascular barrier-enhancing sphingolipid. Sphingolipids 309-321 cystic fibrosis transmembrane conductance regulator Mus musculus 0-51 25006445-2 2014 Cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel expressed in both epithelial and endothelial cells, regulates the organization of tight junctions between epithelial cells and has also been implicated in the transport of sphingosine-1 phosphate (S1P), a vascular barrier-enhancing sphingolipid. Sphingolipids 309-321 cystic fibrosis transmembrane conductance regulator Mus musculus 53-57