PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8504036-5	1993	Cholesterol and sphingolipid synthesis are regulated by the rate-limiting enzymes HMG CoA reductase and serine palmitoyl transferase (SPT), respectively.	Sphingolipids	16-28	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	82-99	
8504036-7	1993	Topical application of HMG CoA reductase or SPT inhibitors after acetone treatment delays barrier repair, providing further evidence for a role of cholesterol and sphingolipids in epidermal barrier function.	Sphingolipids	163-176	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	23-40	
34711640-3	2022	ETP-ALLs showed increased biosynthesis of phospholipids and sphingolipids, and were specifically sensitive to inhibition of 3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR), the rate-limiting enzyme in the mevalonate pathway.	Sphingolipids	60-73	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	124-164