PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24066068-7	2013	Both dosages of sinomenine significantly decreased the mRNA and protein expression levels of c-Maf, TNF-alpha and IFN-gamma, which elevated in TNBS-induced colitis.	sinomenine	16-26	interferon gamma	Mus musculus	114-123	
7848335-2	1994	Sinomenine markedly decreased prostaglandin E2 and leukotriene C4 synthesis of macrophages stimulated by zymosan or calcium ionophore and also significantly inhibited the nitric oxide production of RAW 264.7 cells activated by interferon-gamma/lipopolysaccharide.	sinomenine	0-10	interferon gamma	Mus musculus	227-243	
23650707-10	2013	The concentration of anti-OVA IgE, IL-4 and IFN-gamma in the serum and T-bet and GATA3 expression levels of sinomenine treatment group were lower than those of allergic rhinitis group.	sinomenine	108-118	interferon gamma	Mus musculus	44-53	
17386408-6	2007	Moreover, treatments with sinomenine (100 mg/kg and 200 mg/kg) decreased the up-regulated mRNA and protein levels of tumour necrosis factor-alpha(TNF-alpha) and interferon-gamma (IFN-gamma) caused by TNBS.	sinomenine	26-36	interferon gamma	Mus musculus	161-177	
17386408-6	2007	Moreover, treatments with sinomenine (100 mg/kg and 200 mg/kg) decreased the up-regulated mRNA and protein levels of tumour necrosis factor-alpha(TNF-alpha) and interferon-gamma (IFN-gamma) caused by TNBS.	sinomenine	26-36	interferon gamma	Mus musculus	179-188	
17386408-7	2007	Our findings suggest that sinomenine attenuates TNBS-induced colitis in mice and the therapeutic mechanism might be related to the reduction of up-regulated colonic TNF-alpha and IFN-gamma production caused by TNBS.	sinomenine	26-36	interferon gamma	Mus musculus	179-188