PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32879146-10	2020	In TAK1 silencing cells, the levels of MMPs and p65 phosphorylation of SN-treatedcells were lower than DMSO-treated cells, indicating that blocking interaction was not a unique way for SN to inhibit MMPs levels.	sinomenine	71-73	RELA proto-oncogene, NF-kB subunit	Homo sapiens	48-51	
31356903-14	2019	CCAT1 overexpression, which per se induced inflammatory lesions, negated the positive effects of sinomenine with the restored phosphorylation of p65, IkappaBalpha, and p38MAPK.	sinomenine	97-107	RELA proto-oncogene, NF-kB subunit	Homo sapiens	145-148	
23047501-7	2012	Furthermore, sinomenine inhibited the phosphorylations of extracellular signal-regulated kinase (ERK) and p38 MAPKs as well as the translocation of NF-kappaB p65 through reduced IkappaBalpha degradation.	sinomenine	13-23	RELA proto-oncogene, NF-kB subunit	Homo sapiens	158-161	
29442025-11	2017	Furthermore, sinomenine prevented IL-1beta-induced TLR4, MyD88 and p-NF-kappaB p65 expression.	sinomenine	13-23	RELA proto-oncogene, NF-kB subunit	Homo sapiens	79-82