PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27882945-3	2016	In this study, we found that tunicamycin-induced ER stress increased serum free fatty acid (FFA) and impaired glucose tolerance, elevated the mRNA levels of GRP78, Chop, ATF2 and caspase 3, but reduced adiponectin mRNA level in white adipose tissue.	Tunicamycin	29-40	caspase 3	Mus musculus	179-188	
29684334-5	2018	GADD45beta-I significantly attenuated TM-induced toxicity via inhibiting apoptotic cell death, as evidenced by decreased number of TUNEL-positive cells and reduced caspase-3 activity.	Tunicamycin	38-40	caspase 3	Mus musculus	164-173	
25620058-9	2015	Tunicamycin-induced caspase-3 activation was also shown on PD12 but to a much lesser degree and mainly located in the dentate gyrus of the hippocampus, deep cerebellar nuclei and pons.	Tunicamycin	0-11	caspase 3	Mus musculus	20-29	
25620058-8	2015	In PD4 mice, tunicamycin-induced caspase-3 activation was observed in layer II of the parietal and optical cortex, CA1-CA3 and the subiculum of the hippocampus, the cerebellar external germinal layer and the superior/inferior colliculus.	Tunicamycin	13-24	caspase 3	Mus musculus	33-42	
25968954-6	2015	Moreover, tunicamycin challenge dramatically facilitated myocardial apoptosis as manifested by increased Bax, caspase 9, and caspase 12 protein levels, as well as elevated caspase 3 activity.	Tunicamycin	10-21	caspase 3	Mus musculus	172-181	
23364800-7	2013	Similarly, the induction of apoptosis was higher in tunicamycin-treated male mice, as measured by the activation of Bax and caspase-3.	Tunicamycin	52-63	caspase 3	Mus musculus	124-133	
33209651-12	2013	Down regulated expression of caspase-9 and caspase-3 proposes a non-canonical pathway of cell death during "ER stress" induced by nano-formulated Tunicamycin.	Tunicamycin	146-157	caspase 3	Mus musculus	43-52	
33272572-2	2021	In comparison to their normal counterparts, Optn-deficient mouse embryonic fibroblasts showed significantly higher cell death and caspase-3 activation upon treatment with tunicamycin and thapsigargin, inducers of ER stress.	Tunicamycin	171-182	caspase 3	Mus musculus	130-139	
23041155-4	2012	In mouse cultured hippocampal HT22 cells, imipramine inhibited cell death and caspase-3 activation induced by tunicamycin, although it did not alter the elevated expressions of 78 kDa glucose-regulated protein (GRP78) and C/EBP-homologous protein (CHOP).	Tunicamycin	110-121	caspase 3	Mus musculus	78-87