PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30637701-14	2018	Interestingly, nano-formulated tunicamycin is three times more potent in inhibiting the cell cycle progression than the native tunicamycin and is supported by downregulation of the ratio of phospho-p53 to total-p53 as well as phospho-Rb to total Rb.	Tunicamycin	31-42	tumor protein p53	Homo sapiens	198-201	
18838865-3	2008	Here, we show by epistatic analysis that p53 inhibition results in a maximum level of autophagy that cannot be further enhanced by a variety of different autophagy inducers including lithium, tunicamycin-induced stress of the endoplasmic reticulum (ER) or inhibition of Bcl-2 and Bcl-X(L) with the BH3 mimetic ABT737.	Tunicamycin	192-203	tumor protein p53	Homo sapiens	41-44	
18838865-4	2008	Chemical inducers of autophagy (including rapamycin, lithium, tunicamycin and ABT737) induced rapid depletion of the p53 protein.	Tunicamycin	62-73	tumor protein p53	Homo sapiens	117-120	
29488603-8	2018	Flow cytometry assays indicated that miR-124 transfection attenuated apoptosis resistance of osteosarcoma to tunicamycin, potentially via the downregulation of P53 and Bcl-2 apoptosis regulator expression.	Tunicamycin	109-120	tumor protein p53	Homo sapiens	160-163	
18604159-6	2008	Several distinct autophagy inducers (e.g., starvation, rapamycin, lithium, tunicamycin and thapsigargin) stimulate the rapid degradation of p53.	Tunicamycin	75-86	tumor protein p53	Homo sapiens	140-143	
30637701-14	2018	Interestingly, nano-formulated tunicamycin is three times more potent in inhibiting the cell cycle progression than the native tunicamycin and is supported by downregulation of the ratio of phospho-p53 to total-p53 as well as phospho-Rb to total Rb.	Tunicamycin	31-42	tumor protein p53	Homo sapiens	211-214	
29130967-6	2017	The mutant p53 cell lines were treated with tunicamycin to induce ERS and rapamycin in order to inhibit mTOR.	Tunicamycin	44-55	tumor protein p53	Homo sapiens	11-14	
28720827-9	2017	In the SH-SY5Y human cells, tunicamycin (TM), a PERK activator, promoted transcription of hsp27; and necrosis induced by glutamate could be rescued by TM, associated with reduced p53 accumulation.	Tunicamycin	28-39	tumor protein p53	Homo sapiens	179-182	
24008518-9	2013	Protein levels of both p53 and glucosidase II were increased in response to UV irradiation but decreased in response to tunicamycin-induced ER stress.	Tunicamycin	120-131	tumor protein p53	Homo sapiens	23-26	
19242657-0	2009	Tunicamycin suppresses cisplatin-induced HepG2 cell apoptosis via enhancing p53 protein nuclear export.	Tunicamycin	0-11	tumor protein p53	Homo sapiens	76-79	
22859938-6	2012	Tunicamycin or brefeldin A, two ER stress inducers, increased p53 expression in MCF-7 and Hela cells.	Tunicamycin	0-11	tumor protein p53	Homo sapiens	62-65	
19699254-4	2009	Capsaicin also induced degradation of tumor suppressor p53; this effect was enhanced by the ER stressor tunicamycin.	Tunicamycin	104-115	tumor protein p53	Homo sapiens	55-58	
19242657-4	2009	In order to further explore the mechanism underlying tumor resistance to cisplatin, we observed that increased nuclear export of endogenous p53 protein by pharmacological inducers of ER stress, such as tunicamycin, was associated with the suppression of cisplatin-induced apoptosis.	Tunicamycin	202-213	tumor protein p53	Homo sapiens	140-143