PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2256915-4 1990 Alpha-anomeric preference in lactate production from glucose was observed in glucokinase-loaded erythrocytes, whereas the beta anomer of glucose was more rapidly utilized than the alpha anomer in intact and unloaded erythrocytes. Lactic Acid 29-36 glucokinase Homo sapiens 77-88 3026341-4 1986 At constant 5 mM-glucose and 2 mM-lactate concentrations insulin increased glucokinase flux by 35%; it decreased glucose-6-phosphatase flux from glycogen by 50%, from lactate by 15% and reverse flux from external glucose by 65%, i.e. overall by 40%. Lactic Acid 34-41 glucokinase Homo sapiens 75-86 6257679-6 1981 The addition to the medium of glucose, fructose, pyruvate, or lactate enhanced the insulin-induced increase in glucokinase, but only fructose, pyruvate, and lactate increased the activity of the enzyme in the absence of insulin. Lactic Acid 157-164 glucokinase Homo sapiens 111-122 33920410-6 2021 We show here that overexpression of GCK inhibits the proliferation of HCC cells via induction of intracellular lactate accumulation and subsequently causes energy crisis due to NAD+ depletion. Lactic Acid 111-118 glucokinase Homo sapiens 36-39 6257679-6 1981 The addition to the medium of glucose, fructose, pyruvate, or lactate enhanced the insulin-induced increase in glucokinase, but only fructose, pyruvate, and lactate increased the activity of the enzyme in the absence of insulin. Lactic Acid 62-69 glucokinase Homo sapiens 111-122 11600496-6 2002 Additional evidence for activation of distinct pathways of glycogen synthesis by GK and targeting subunits is provided by the additive effect of co-overexpression of the two types of proteins upon glycogen synthesis and a much larger stimulation of glucose utilization, glucose transport, and lactate production elicited by GK. Lactic Acid 293-300 glucokinase Homo sapiens 81-83