PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25681332-10 2015 The findings reported in this study suggest a novel mechanism for the anti-inflammatory properties of the cyclopentenone PGs through inhibition of caspase-1 and the inflammasome. cyclopentenone 106-120 caspase 1 Mus musculus 147-156 25681332-3 2015 We report that the eicosanoid 15-deoxy-Delta(12,14)-PGJ2 (15d-PGJ2) and related cyclopentenone PGs inhibit caspase-1 activation by the NLR family leucine-rich repeat protein (NLRP)1 and NLRP3 inflammasomes. cyclopentenone 80-94 caspase 1 Mus musculus 107-116