PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34326690-0 2021 Cantharidin inhibits osteosarcoma proliferation and metastasis by directly targeting miR-214-3p/DKK3 axis to inactivate beta-catenin nuclear translocation and LEF1 translation. Cantharidin 0-11 microRNA 214 Homo sapiens 85-92 34326690-7 2021 Cantharidin suppressed viabilities, migration and invasion, while promoted cell cycle arrest and apoptosis in 143B and U-2 OS cells via down-regulating miR-214-3p to up-regulate DKK3, thus inhibited p-GSK-3beta expression, beta-catenin nuclear translocation and LEF1 translation. Cantharidin 0-11 microRNA 214 Homo sapiens 152-159 25962755-0 2015 Cantharidin inhibits cell proliferation and promotes apoptosis in tongue squamous cell carcinoma through suppression of miR-214 and regulation of p53 and Bcl-2/Bax. Cantharidin 0-11 microRNA 214 Homo sapiens 120-127 25962755-10 2015 Cantharidin markedly weakened miR-214 expression level, activated p53 protein expression, and suppressed the Bcl-2/Bax signaling pathway in Tca8113 cells. Cantharidin 0-11 microRNA 214 Homo sapiens 30-37 25962755-12 2015 However, the overexpression of miR-214 reduced the anticancer effect of cantharidin on the proliferation and apoptosis of TSCC Tca8113 cells, inhibited p53 protein expression, and increased the Bcl-2/Bax signaling pathway. Cantharidin 72-83 microRNA 214 Homo sapiens 31-38