PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15785805-9	2005	In representative cases, the covalent adducts (syn and anti) formed by reaction of the benzylic carbocations derived from diol epoxides and dihydrodiols with methoxide and methanethiolate anions were studied.	diol epoxides	122-135	synemin	Homo sapiens	47-50	
11322184-2	2001	The tetraols formed by the trans ring opening of the diol epoxides during hydrolysis yield product ion spectra specific for the syn and anti configurations of their precursor diol epoxides.	diol epoxides	53-66	synemin	Homo sapiens	128-131	
15058949-3	2004	The latter include the corresponding o-catechols, trans-dihydrodiols, and the corresponding anti- and syn-diol epoxides.	diol epoxides	106-119	synemin	Homo sapiens	102-105	
2497101-2	1989	Treatment of diploid human fibroblasts with stereoisomeric benzo[alpha]pyrene anti and syn diol epoxides has been shown to induce anchorage-independent clones of cells with a dose dependence and frequency [(0.5-12) X 10(-4)] not significantly different from mutations at the hypoxanthine-guanine phosphoribosyltransferase locus [(1-8) X 10(-4)] in these cells.	diol epoxides	91-104	synemin	Homo sapiens	87-90	
9525277-5	1998	GSTP1-1/V-105 was found to be more active than GSTP1-1/I-105 in conjugation reactions with the bulky diol epoxides of PAH, being up to 3-fold as active towards the anti- and syn-diol epoxide enantiomers with R-absolute configuration at the benzylic oxiranyl carbon.	diol epoxides	101-114	synemin	Homo sapiens	174-177	
9525277-8	1998	With the syn-diol epoxides, such a correlation was observed with alanine, valine and isoleucine, whereas tryptophan was associated with increased kcat/Km values.	diol epoxides	13-26	synemin	Homo sapiens	9-12	
8924621-3	1996	Although this pathway suppresses the formation of the PAH anti- and syn-diol epoxides (ultimate carcinogens), the process of autoxidation is anticipated to yield reactive oxygen species (ROS).	diol epoxides	72-85	synemin	Homo sapiens	68-71