PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16190985-2 2005 Within eosinophils, unlike lymphocytes, IL-4 is stored in granules (termed specific granules) and can be rapidly released by brefeldin A (BFA)-inhibitable mechanisms upon stimulation with eotaxin, a chemokine that activates eosinophils. Brefeldin A 125-136 C-C motif chemokine ligand 11 Homo sapiens 188-195 16190985-2 2005 Within eosinophils, unlike lymphocytes, IL-4 is stored in granules (termed specific granules) and can be rapidly released by brefeldin A (BFA)-inhibitable mechanisms upon stimulation with eotaxin, a chemokine that activates eosinophils. Brefeldin A 138-141 C-C motif chemokine ligand 11 Homo sapiens 188-195 16190985-8 2005 As documented with quantitative electron microscopy, eotaxin-induced significant formation of EoSVs while BFA pretreatment suppressed eotaxin-elicited EoSVs. Brefeldin A 106-109 C-C motif chemokine ligand 11 Homo sapiens 134-141 11290754-6 2001 IL-5 enhanced eotaxin-induced IL-4 release, which was mediated by G protein-coupled CCR3 receptors, detectable as early as 5 min and maximum within 1 h. IL-4 release was not diminished by transcription or protein synthesis inhibitors, but was suppressed by brefeldin A, an inhibitor of vesicle formation. Brefeldin A 257-268 C-C motif chemokine ligand 11 Homo sapiens 14-21