PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23468973-2 2013 BCP crystals induce in vitro catabolic responses with the production of metalloproteases and inflammatory cytokines such as interleukin-1 (IL-1). bcp 0-3 interleukin 1 complex Mus musculus 139-143 23468973-3 2013 In vivo, IL-1 production induced by BCP crystals is both dependant and independent of NLRP3 inflammasome. bcp 36-39 interleukin 1 complex Mus musculus 9-13 23468973-4 2013 We aimed to clarify 1/ the role of BCP crystals in cartilage destruction and 2/ the role of IL-1 and NLRP3 inflammasome in cartilage degradation related to BCP crystals. bcp 156-159 interleukin 1 complex Mus musculus 92-96