PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10484417-8	1999	Interestingly, stimulation of the cAMP pathway before cGMP pathway activation resulted in a significant increase in sensitivity and a difference in relaxation parameters between PLB- and wild-type aortas.	Cyclic AMP	34-38	phospholamban	Mus musculus	178-181	
11854448-7	2002	The association was inhibited by cAMP-dependent phosphorylation of the PLN fusion protein and by usage of anti-PLN monoclonal antibody.	Cyclic AMP	33-37	phospholamban	Mus musculus	71-74	
11854448-7	2002	The association was inhibited by cAMP-dependent phosphorylation of the PLN fusion protein and by usage of anti-PLN monoclonal antibody.	Cyclic AMP	33-37	phospholamban	Mus musculus	111-114	
31373621-11	2020	The activity of PLB could be inhibited by beta1-AR-cAMP-PKA pathway through PKA-mediated protein phosphorylation.	Cyclic AMP	51-55	phospholamban	Mus musculus	16-19	
33463061-11	2021	Mechanistically, these optimized effects were associated with enhanced the adenosine (cAMP)-protein kinase A (PKA) pathway, which upregulated phosphorylate-phospholamban (p-PLN) (Ser16) and promoted sarco/endoplasmic reticulum Ca2+ ATPase (Serca) and Ryanodine Receptor 2 (RyR2) expression in the sarcoplasmic reticulum (SR), and ultimately restored Ca2+ handling in response to sepsis.	Cyclic AMP	86-90	phospholamban	Mus musculus	173-176	
33463061-15	2021	CONCLUSIONS: Our data demonstrated that activation of TLR7 protected against sepsis-induced cardiac dysfunction through promoting cAMP-PKA-PLN pathway, and we revealed that TLR7 might be a novel therapeutic target to block the septic cardiomyopathy and support systolic function during sepsis.	Cyclic AMP	130-134	phospholamban	Mus musculus	139-142	
31228183-13	2020	CONCLUSION: Single dose levosimendan prevented doxorubicin cardiotoxicity through a cAMP-PKA-PLN pathway, highlighting the role of inotropy in doxorubicin cardiotoxicity.	Cyclic AMP	84-88	phospholamban	Mus musculus	93-96	
21903937-9	2011	CONCLUSIONS: PDE4D regulates basal cAMP levels in SR microdomains containing SERCA2a-PLN, but not L-type Ca2+ channels or ryanodine receptor.	Cyclic AMP	35-39	phospholamban	Mus musculus	85-88