PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6928683-1	1980	Incubation of reticulocyte lysates with low levels of double-stranded (ds) RNA (1-20 ng/ml) activates a cAMP-independent protein kinase (dsI) that phosphorylates the alpha-subunit (M(r) 38,000) of initiation factor 2 (eIF-2) and produces an inhibition of protein chain initiation similar to that caused by heme deficiency.	Cyclic AMP	104-108	eukaryotic translation initiation factor 2 subunit beta	Homo sapiens	218-223	
6292906-1	1982	Protein synthesis initiation in reticulocyte lysates is inhibited by low concentrations (1-20 ng/ml) of double-stranded RNA (ds RNA) due to the activation of a ds RNA-dependent cAMP-independent protein kinase (ds I) that phosphorylates the alpha subunit of the eukaryotic initiation factor eIF-2.	Cyclic AMP	177-181	eukaryotic translation initiation factor 2 subunit beta	Homo sapiens	290-295	
274704-9	1978	Untreated crude ribosomes also contain cyclic AMP-independent protein kinase activities that phosphorylate the middle polypeptide (49,000 daltons) of eIF-2 and several polypeptide subunits of eIF-3 (160,000, 125,000, and 65,000 daltons); these kinase activities are not affected by double-stranded RNA and do not inhibit protein synthesis.	Cyclic AMP	39-49	eukaryotic translation initiation factor 2 subunit beta	Homo sapiens	150-155	
223849-2	1979	The inhibitor (active eIF-2 kinase), a cAMP-independent protein kinase, catalyzes the phosphorylation by ATP of the small subunit of the polypeptide chain initiation factor eIF-2.	Cyclic AMP	39-43	eukaryotic translation initiation factor 2 subunit beta	Homo sapiens	22-27	
223849-2	1979	The inhibitor (active eIF-2 kinase), a cAMP-independent protein kinase, catalyzes the phosphorylation by ATP of the small subunit of the polypeptide chain initiation factor eIF-2.	Cyclic AMP	39-43	eukaryotic translation initiation factor 2 subunit beta	Homo sapiens	173-178	
279901-8	1978	The activation of I(GSSG) is accompanied by an increased cyclic AMP-independent protein kinase activity which phosphorylates the 38,000-dalton component (alpha subunit) of eIF-2; however, GSSG treatment of supernates does not alter the activity of the cyclic AMP-independent protein kinase activity that phosphorylates the 49,000-dalton polypeptide component (beta subunit) of eIF-2.	Cyclic AMP	57-67	eukaryotic translation initiation factor 2 subunit beta	Homo sapiens	172-177