PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31162799-2	2019	In this study, by performing miRNA genomics and loss- and gain-of-function assays in dibutyryl-cAMP-treated GBM cells, we identified a critical negative regulator, hsa-miR-1275, that modulates a set of genes involved in cancer progression, stem cell maintenance, and cell maturation and differentiation.	Cyclic AMP	95-99	microRNA 1275	Homo sapiens	164-176	
31162799-5	2019	Furthermore, decreased miR-1275 expression and induction of GFAP expression were also observed in dibutyryl-cAMP-treated primary cultured GBM cells.	Cyclic AMP	108-112	microRNA 1275	Homo sapiens	23-31	
31162799-6	2019	In a patient-derived glioma stem cell tumor model, a cAMP elevator and an inhibitor of H3K27me3 methyltransferase inhibited tumor growth, induced differentiation, and reduced expression of miR-1275.	Cyclic AMP	53-57	microRNA 1275	Homo sapiens	189-197	
31162799-7	2019	In summary, our study shows that epigenetic inhibition of miR-1275 by the cAMP/PKA/PRC2/H3K27me3 pathway mediates glial induction of GBM cells, providing a new mechanism and novel targets for differentiation-inducing therapy.	Cyclic AMP	74-78	microRNA 1275	Homo sapiens	58-66