PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30659943-13	2019	CONCLUSIONS: DRA is acutely stimulated by cAMP by a process that is CFTR-dependent, but appears to be one of multiple regulatory effects of CFTR that does not require CFTR activity.	Cyclic AMP	42-46	solute carrier family 26 member 3	Homo sapiens	13-16	
30659943-0	2019	cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity.	Cyclic AMP	0-4	solute carrier family 26 member 3	Homo sapiens	16-23	
30659943-2	2019	An area that has continued to be poorly understood is related to DRA regulation in acute adenosine 3",5"-cyclic monophosphate (cAMP)-related diarrheas, in which DRA appears to be both inhibited as part of NaCl absorption and stimulated to contribute to increased HCO3- secretion.	Cyclic AMP	89-125	solute carrier family 26 member 3	Homo sapiens	65-68	
12651923-9	2003	cAMP-insensitive Cl--HCO3- exchange mediated by hDRA gained modest cAMP sensitivity when co-expressed with cystic fibrosis transmembrane conductance regulator (CFTR).	Cyclic AMP	0-4	solute carrier family 26 member 3	Homo sapiens	48-52	
30659943-2	2019	An area that has continued to be poorly understood is related to DRA regulation in acute adenosine 3",5"-cyclic monophosphate (cAMP)-related diarrheas, in which DRA appears to be both inhibited as part of NaCl absorption and stimulated to contribute to increased HCO3- secretion.	Cyclic AMP	89-125	solute carrier family 26 member 3	Homo sapiens	161-164	
30659943-2	2019	An area that has continued to be poorly understood is related to DRA regulation in acute adenosine 3",5"-cyclic monophosphate (cAMP)-related diarrheas, in which DRA appears to be both inhibited as part of NaCl absorption and stimulated to contribute to increased HCO3- secretion.	Cyclic AMP	127-131	solute carrier family 26 member 3	Homo sapiens	65-68	
30659943-2	2019	An area that has continued to be poorly understood is related to DRA regulation in acute adenosine 3",5"-cyclic monophosphate (cAMP)-related diarrheas, in which DRA appears to be both inhibited as part of NaCl absorption and stimulated to contribute to increased HCO3- secretion.	Cyclic AMP	127-131	solute carrier family 26 member 3	Homo sapiens	161-164	
30659943-3	2019	Different cell models expressing DRA have shown that cAMP inhibits, stimulates, or does not affect its activity.	Cyclic AMP	53-57	solute carrier family 26 member 3	Homo sapiens	33-36	
30659943-4	2019	METHODS: This study re-evaluated cAMP regulation of DRA using new tools, including a successful knockout cell model, a specific DRA inhibitor (DRAinh-A250), specific antibodies, and a transport assay that did not rely on nonspecific inhibitors.	Cyclic AMP	33-37	solute carrier family 26 member 3	Homo sapiens	52-55	
30659943-8	2019	cAMP (forskolin) acutely stimulated DRA activity in human colonoids and Caco-2 cells.	Cyclic AMP	0-4	solute carrier family 26 member 3	Homo sapiens	36-39	
30659943-11	2019	When CFTR was expressed in HEK293/DRA cells, cAMP also stimulated DRA activity.	Cyclic AMP	45-49	solute carrier family 26 member 3	Homo sapiens	34-37	
30659943-11	2019	When CFTR was expressed in HEK293/DRA cells, cAMP also stimulated DRA activity.	Cyclic AMP	45-49	solute carrier family 26 member 3	Homo sapiens	66-69	
30659943-12	2019	In all cases, cAMP stimulation of DRA was not inhibited by CFTRinh-172.	Cyclic AMP	14-18	solute carrier family 26 member 3	Homo sapiens	34-37	
19056765-7	2009	Coupled aNHE and DRA activities were inhibited by increased cellular cAMP and calcium and were associated with synaptotagmin I-dependent, clathrin-mediated endocytosis.	Cyclic AMP	69-73	solute carrier family 26 member 3	Homo sapiens	17-20	
12651923-9	2003	cAMP-insensitive Cl--HCO3- exchange mediated by hDRA gained modest cAMP sensitivity when co-expressed with cystic fibrosis transmembrane conductance regulator (CFTR).	Cyclic AMP	67-71	solute carrier family 26 member 3	Homo sapiens	48-52	
8657566-1	1996	The transcription factor hXBP-1 belongs to the family of basic region/leucine zipper (bZIP) proteins and interacts with the cAMP responsive element (CRE) of the major histocompatibility complex (MHC) class II A alpha, DR alpha and DP beta genes.	Cyclic AMP	124-128	solute carrier family 26 member 3	Homo sapiens	218-226	
35076190-2	2022	NHE3 and DRA are highly regulated by changes in second messengers, cAMP, cGMP and Ca2+.	Cyclic AMP	67-71	solute carrier family 26 member 3	Homo sapiens	9-12	
2788889-3	1989	The enhancer has been localized to a 116-base-pair BstXI/Dra I restriction enzyme fragment, which lacks immunoglobulin octamer and kappa B enhancer motifs but does contain a consensus cAMP-response element (CRE).	Cyclic AMP	184-188	solute carrier family 26 member 3	Homo sapiens	57-60