PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26202629-9	2016	KAT2B encodes a transcriptional regulator in the cyclic adenosine monophosphate and dopamine signaling pathways, and rs9829896-C was associated with expression of genes in these pathways: reduced CREBBP expression (P = 0.011) and increased OPRM1 expression (P = 0.016), both in AAs only.	Cyclic AMP	49-79	lysine acetyltransferase 2B	Homo sapiens	0-5	
27774669-5	2017	And we further characterized P300/cyclic adenosine monophosphate response element binding protein-binding protein-associated factor (PCAF) and Sirtuin 7 as the enzymes regulating K323 acetylation from both directions in liver cancer cells.	Cyclic AMP	34-64	lysine acetyltransferase 2B	Homo sapiens	133-137	
30305648-4	2018	Here, we show that the accessibility of beta-catenin to the promoter region of its target genes is regulated by developmental stage-specific histone acetyltransferases (HATs), lysine acetyltransferase 2B (KAT2B), and cAMP-response element-binding protein (CREB)-binding protein (CBP).	Cyclic AMP	217-221	lysine acetyltransferase 2B	Homo sapiens	205-210	
22150271-7	2012	Acetylation assays show that HMGN3a stimulates the ability of PCAF [p300/CREB (cAMP-response-element-binding protein)-binding protein-associated factor] to acetylate nucleosomal H3 in vitro, whereas HMGN3b does not.	Cyclic AMP	79-83	lysine acetyltransferase 2B	Homo sapiens	62-66	
21413932-4	2011	RANKL stimulates NFATc1 acetylation via HATs (histone acetyltransferases), such as p300 and PCAF [p300/CREB (cAMP-response-element-binding protein)-binding protein-associated factor], thereby stabilizing NFATc1 proteins.	Cyclic AMP	109-113	lysine acetyltransferase 2B	Homo sapiens	92-96	
19522704-5	2009	Furthermore, we found that this repression could be relieved by P/CAF (p300/CBP-associated factor) in a dose-dependent manner, but not by CBP [CREB (cAMP-response-element-binding protein)-binding protein].	Cyclic AMP	149-153	lysine acetyltransferase 2B	Homo sapiens	64-69	
20631054-5	2010	Dioxin induced the recruitment of AHR and the transcriptional coactivators p300 and p300/cAMP response element-binding protein binding protein-associated factor (PCAF) to the CYP1B1 enhancer in HepG2 cells but failed to induce recruitment of RNA polymerase II (polII) or the TATA binding protein (TBP) and acetylations of histones 3 and 4 or methylation of histone 3 at the promoter.	Cyclic AMP	89-93	lysine acetyltransferase 2B	Homo sapiens	162-166	
20352046-10	2010	Of note, cAMP recruited pCREB, CBP/p300, and PCAF to the promoter whereas T(3) caused dissociation of NCoR/SMRT and HDAC3.	Cyclic AMP	9-13	lysine acetyltransferase 2B	Homo sapiens	45-49	
20144149-7	2010	Histone acetyltransferases such as p300 and P/CAF [p300/CREB (cAMP-response-element-binding protein)-binding protein-associated factor] increased induction of the MMP28 promoter by Sp1.	Cyclic AMP	62-66	lysine acetyltransferase 2B	Homo sapiens	44-49	
19522704-5	2009	Furthermore, we found that this repression could be relieved by P/CAF (p300/CBP-associated factor) in a dose-dependent manner, but not by CBP [CREB (cAMP-response-element-binding protein)-binding protein].	Cyclic AMP	149-153	lysine acetyltransferase 2B	Homo sapiens	71-97	
18377363-7	2008	Several subunits of the P/CAF {p300/CBP [CREB (cAMP-response-element-binding protein)-binding protein]-associated factor} complex, including ADA3, ADA2alpha/beta and P/CAF, showed co-localization with ANCO-1 nuclear dots, indicating an in vivo association of ANCO-1 with the P/CAF complex.	Cyclic AMP	47-51	lysine acetyltransferase 2B	Homo sapiens	24-29	
16887930-8	2006	Dephosphorylation of its AF-1 made TR4 an activator due to its selective recruitment of coactivator, P300/cyclic AMP-responsive element binding protein-binding protein-associated factor (PCAF).	Cyclic AMP	106-116	lysine acetyltransferase 2B	Homo sapiens	187-191	
18425496-2	2008	Normally, these factors are transiently activated by specific external signals which induce their dissociation from inhibitors of kappaB (IkappaB) and subsequent translocation to the nucleus where p65 links to the cyclic adenosine monophosphate response element binding protein (CBP)-p300 and P/CAF coactivators that are essential for its transcriptional activity.	Cyclic AMP	214-244	lysine acetyltransferase 2B	Homo sapiens	293-298	
17496784-3	2007	The NF-kappaB activation appears to result from the enhancer formation including NF-kappaB and lysine acetyl transferases such as p300, CREB (cyclic AMP-responsive element binding protein)-binding protein (CBP), and/or p300/CBP associating factor (PCAF).	Cyclic AMP	142-152	lysine acetyltransferase 2B	Homo sapiens	219-246	
17496784-3	2007	The NF-kappaB activation appears to result from the enhancer formation including NF-kappaB and lysine acetyl transferases such as p300, CREB (cyclic AMP-responsive element binding protein)-binding protein (CBP), and/or p300/CBP associating factor (PCAF).	Cyclic AMP	142-152	lysine acetyltransferase 2B	Homo sapiens	248-252	
15025563-5	2004	Recently, a dominant-negative construct of the transcriptional co-activator P/CAF [p300/CBP-associated factor, where CBP stands for CREB (cAMP-response-element-binding protein)-binding protein] was shown to inhibit involucrin expression in immortalized keratinocytes [Kawabata, Kawahara, Kanekura, Araya, Daitoku, Hata, Miura, Fukamizu, Kanzaki, Maruyama and Nakajima (2002) J. Biol.	Cyclic AMP	138-142	lysine acetyltransferase 2B	Homo sapiens	76-81	
16227401-6	2005	Thirty-five N-substituted analogues inhibited both p300/cyclic AMP-responsive element binding protein-binding protein-associated factor (PCAF) and p300 (1 to >50 micromol/L, respectively) and the growth of a panel of human tumor cell lines (50% growth inhibition, 0.8 to >50 micromol/L).	Cyclic AMP	56-66	lysine acetyltransferase 2B	Homo sapiens	137-141	
15025563-5	2004	Recently, a dominant-negative construct of the transcriptional co-activator P/CAF [p300/CBP-associated factor, where CBP stands for CREB (cAMP-response-element-binding protein)-binding protein] was shown to inhibit involucrin expression in immortalized keratinocytes [Kawabata, Kawahara, Kanekura, Araya, Daitoku, Hata, Miura, Fukamizu, Kanzaki, Maruyama and Nakajima (2002) J. Biol.	Cyclic AMP	138-142	lysine acetyltransferase 2B	Homo sapiens	83-109	
9163323-8	1997	This suggests that, in the context of the X2 element, CREB requires a close interaction with CAF to achieve both basal and cAMP-dependent transcriptional activation.	Cyclic AMP	123-127	lysine acetyltransferase 2B	Homo sapiens	93-96	
12726776-1	2003	Coactivators such as cyclic AMP-response-element binding protein (CREB)-binding protein (CBP) and p300/CBP associated factor (P/CAF) play a crucial role in coordinating and cointegrating eukaryotic transcription.	Cyclic AMP	21-31	lysine acetyltransferase 2B	Homo sapiens	126-131	
9751061-4	1998	Furthermore, the histone acetyltransferase functions of CBP or p/CAF are required for Pit-1 function that is stimulated by cyclic AMP or growth factors, respectively.	Cyclic AMP	123-133	lysine acetyltransferase 2B	Homo sapiens	63-68	
12726776-1	2003	Coactivators such as cyclic AMP-response-element binding protein (CREB)-binding protein (CBP) and p300/CBP associated factor (P/CAF) play a crucial role in coordinating and cointegrating eukaryotic transcription.	Cyclic AMP	21-31	lysine acetyltransferase 2B	Homo sapiens	98-124