PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9310369-0 1997 Rapid induction of the Grp78 gene by cooperative actions of okadaic acid and heat-shock in 9L rat brain tumor cells--involvement of a cAMP responsive element-like promoter sequence and a protein kinase A signaling pathway. Cyclic AMP 134-138 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 23-28 1655795-0 1991 Stimulation of GRP78 gene transcription by phorbol ester and cAMP in GH3 pituitary cells. Cyclic AMP 61-65 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 15-20 1655795-5 1991 In GH3 cells, optimal induction of GRP78 and translational accommodation depended on cAMP elevation and phorbol ester. Cyclic AMP 85-89 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 35-40 1655795-6 1991 GRP78 mRNA was induced 3-6-fold with A23187 alone as compared with 12-20-fold with ionophore plus cAMP-elevating agent and phorbol ester, but was not markedly induced without A23187. Cyclic AMP 98-102 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 0-5 1655795-7 1991 GRP78 gene transcription in nuclei isolated from A23187-treated cells was increased 2-4-fold by cAMP and phorbol ester. Cyclic AMP 96-100 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 0-5 1655795-8 1991 A nucleotide sequence homologous to the cAMP-responsive element consensus potentially exists in the promoter region of the GRP78 gene. Cyclic AMP 40-44 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 123-128 1655795-11 1991 Translational accommodation in ionophore-treated GH3 cells is proposed to involve enhanced transcription of GRP78 mRNA promoted by cAMP/phorbol ester in conjunction with preferential polysomal loading of the message. Cyclic AMP 131-135 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 108-113 1944297-9 1991 These results suggest that the expression of GRP78 in thyroid cells is regulated by TSH via cAMP, for which cycloheximide-sensitive protein synthesis might be required, and that more GRP78 might be needed to assist in the synthesis and transport of glycoprotein molecules in TSH-stimulated cells. Cyclic AMP 92-96 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 45-50 2122977-8 1990 In Ca2(+)-deprived GH3 cells, the synthesis of GRP78 was promoted by phorbol ester and cAMP with the extent of induction correlating directly with the degree of translational tolerance to ionophore. Cyclic AMP 87-91 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 47-52 2549056-9 1989 Of the rat tissues examined, only the major steroid-forming organs (adrenal cortex and gonads) had significant levels of immunoreactive, cAMP-responsive SAP, while cAMP-unresponsive immunoreactivity was also detectable in the thymus, spleen, and brain. Cyclic AMP 137-141 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 153-156 2549056-10 1989 Considered together with the biological activity previously demonstrated for SAP in vitro, these data are consistent with its role as a cAMP-dependent, cycloheximide-sensitive modulator of steroid biosynthesis. Cyclic AMP 136-140 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 77-80 30782262-6 2019 In contrast, the expression of GRP78, CHOP, and caspase12 was decreased in SCI rats after cAMP treatment. Cyclic AMP 90-94 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 31-36